4 products were found matching "Cay579070-1"!

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U-0126
U-0126

Item number: Cay70970-1

U-0126 is a MEK inhibitor with IC50 values of 72 nM and 58 nM for MEK1 and MEK2, respectively. It is noncompetitive with respect adenosine triphosphate (ATP) and its phosphorylation target ERK and it shows little to no inhibition against a number of other kinases including PKC, Ab1, Raf, MEKK, ERK, JNK, MKK-3,...
Keywords: 2,3-bis[amino[(2-aminophenyl)thio]methylene]-butanedinitrile
Application: MEK inhibitor
CAS 109511-58-2
MW: 380.5 D
From 60.00€ *
Review
17,20-dimethyl Prostaglandin F1alpha
17,20-dimethyl Prostaglandin F1alpha

Item number: Cay15790-10

17,20-dimethyl Prostaglandin F1alpha (17,20-dimethyl PGF1alpha) is an analog of the limaprost family with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is an analog of PGE1 which is orally active in both rats and guinea pigs. The additional methyl groups in the...
Keywords: 17,20-dimethyl PGF1alpha, 9alpha,11alpha,15S-trihydroxy-17S,20-dimethyl-prost-13E-en-1-oic acid
Application: Bioactive lipid assays
MW: 384.6 D
From 86.00€ *
Review
246C10
246C10

Item number: Cay37907-10

246C10 is an ionizable cationic lipid (pKa = 6.75). It has been used in combination with other lipids in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. Intravenous administration of LNPs containing 246C10 and encapsulating an mRNA reporter selectively accumulate in mouse...
Keywords: 1,1',1'',1'''-[1,4-piperazinediylbis(3,1-propanediylnitrilo)]tetrakis-2-dodecanol
Application: Ionizable cationic lipid, LNP formation
CAS 2635329-26-7
MW: 937.6 D
From 135.00€ *
Review
U-75302
U-75302

Item number: Cay70705-50

U-75302 is an LTB4 receptor antagonist with a Ki of 159 nM on guinea pig lung membranes. This activity is specific for the BLT1 receptor, U-75302 does not antagonize the binding of [3H]-LTB4 to the human BLT2 receptor.Formal Name: 6-(6-(3R-hydroxy-1E,5Z-undecadien-1-yl)-2-pyridinyl)-1,5S-hexanediol. CAS Number:...
Keywords: 6-(6-(3R-hydroxy-1E,5Z-undecadien-1-yl)-2-pyridinyl)-1,5S-hexanediol
Application: LTB4 receptor antagonist
CAS 119477-85-9
MW: 361.5 D
From 117.00€ *
Review