4 products were found matching "Cay15596"!

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Rauwolscine (hydrochloride)
Rauwolscine (hydrochloride)

Item number: Cay15596-100

Rauwolscine is a natural alkaloid that acts as a selective and reversible alpha2-adrenergic receptor antagonist (Ki = 12 nM). It is a stereoisomer of yohimbine, which potently antagonizes both alpha1- and alpha2-adrenergic receptors. Rauwolscine also acts as a receptor antagonist at the serotonin 5-HT2B receptor (Ki...
Keywords: Isoyohimbine, NSC 407307, alpha-Yohimbine, (16beta,17alpha,20alpha)-17-hydroxy-yohimban-16-carboxylic acid, methyl ester,...
Application: Selective, reversible alpha2-adrenergic receptor antagonist
CAS 6211-32-1
MW: 390.9 D
From 50.00€ *
Review
PKA Inhibitor (5-24) (trifluoroacetate salt)
PKA Inhibitor (5-24) (trifluoroacetate salt)

Item number: Cay15996-1

PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki = 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein. It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite. The prominent...
Keywords: PKI (5-24), Protein Kinase A Inhibitor (5-24),...
Application: cAMP-dependent protein kinase (PKA) inhibitor
MW: 2222.4 D
From 98.00€ *
Review
MDV 3100
MDV 3100

Item number: Cay11596-10

MDV 3100 is a non-steroidal androgen receptor antagonist (IC50 = 36 nM). It reduces the efficiency of nuclear translocation of the androgen receptor and impairs both its binding to DNA and the recruitment of coactivators. It is orally available and induces tumor regression in mouse models of castration-resistant...
Keywords: Enzalutamide,...
Application: Androgen receptor antagonist
CAS 915087-33-1
MW: 464.4 D
From 40.00€ *
Review
CAY10684
CAY10684

Item number: Cay15966-1

Prostaglandin E2 (PGE2, Cay-14010) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a G protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10684 is a lactam that acts as a potent EP4 agonist,...
Keywords: (2R)-2-[(1E)-3-(4'-chloro-2'-methyl[1,1'-biphenyl]-3-yl)-3-hydroxy-1-propen-1-yl]-5-oxo-1-pyrrolidineheptanoic acid
Application: EP4 agonist
CAS 493035-81-7
MW: 470 D
From 127.00€ *
Review