Ran Activation Assay Kit

Ran Activation Assay Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NB-81701 30 assays - -

3 - 16 business days*

1,068.00€
 
Configuration-specific monoclonal antibody that recognizes Ran-GTP, but not Ran-GDP. The only... more
Product information "Ran Activation Assay Kit"
Configuration-specific monoclonal antibody that recognizes Ran-GTP, but not Ran-GDP. The only available Ran activation assay kit directly measures the level of Ran-GTP. Providing reliable results with consistent reproducibility than other Ran activation assay kits based on certain downstream signaling pathways. Providing shorter experimental time. Could be used to monitor the activation of Ran in cells and in tissues by immunohistochemistry. Protein function: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. [The UniProt Consortium]
Keywords: RAN, ARA24, GTPase Ran, Ras-like protein TC4, Ras-related nuclear protein, GTP-binding nuclear protein Ran, Androgen receptor-associated protein 24
Supplier: NewEast Biosciences
Supplier-Nr: 81701

Properties

Application: IP/WB G-Protein Activation assay
Species reactivity: vertebrates
Format: Membrane Based

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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