Rac Activation Assay Kit

Rac Activation Assay Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NB-80501 30 assays - -

3 - 16 business days*

1,068.00€
 
Configuration-specific monoclonal anti-Rac-GTP antibody based. This monoclonal antibody... more
Product information "Rac Activation Assay Kit"
Configuration-specific monoclonal anti-Rac-GTP antibody based. This monoclonal antibody specifically recognizes Rac-GTP, but not Rac-GDP. Providing shorter experimental time. Providing reliable results with consistent reproducibility than other Rac activation assay kits. Could be used to monitor the activation of Rac in cells and in tissues by immunohistochemistry Protein function: Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Stimulates PKN2 kinase activity. In concert with RAB7A, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. In glioma cells, promotes cell migration and invasion. [The UniProt Consortium]
Keywords: RAC1, MIG5, TC25, p21-Rac1, Ras-like protein TC25, Cell migration-inducing gene 5 protein, Ras-related C3 botulinum toxin substrate 1
Supplier: NewEast Biosciences
Supplier-Nr: 80501

Properties

Application: IP/WB G-Protein Activation assay
Species reactivity: vertebrates
Format: Membrane Based

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Rac Activation Assay Kit"
Write a review
or to review a product.
Viewed