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STAT5 Inhibitor
STAT5 Inhibitor

Item number: Cay15784-5

Signal Transducers and Activators of Transcriptions (STATs) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. STAT5, which consists of two...
Keywords: Signal Transducers and Activators of Transcription 5, 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide...
Application: Cell permeable STAT5 inhibitor
CAS 285986-31-4
MW: 293.3 D
From 92.00€ *
Review
Ku-0060648
Ku-0060648

Item number: Cay15344-5

Ku-0060648 is an ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK) and an inhibitor of PI3K. In a cell-free assay, it has IC50s of 5, 4, 0.5, 50s of 19 and 39 nM, for DNA-PK and PI3K, respectively, while in SW620 cells, it has an IC50 of 170 nM for DNA-PK but >10,000 nM for PI3K. Ku-0060648 is...
Keywords: 4-ethyl-N-[4-[2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-1-piperazineacetamide
Application: Dual PI3K & DNA-PK inhibitor
CAS 881375-00-4
MW: 582.7 D
From 50.00€ *
Review
Bicyclomycin Benzoate
Bicyclomycin Benzoate

Item number: Cay15384-5

Bicyclomycin benzoate is an antibiotic produced by S. sapporonensis that inhibits Gram-negative bacteria, including E. coli, Klebsiella, Shigella, Salmonella, Citrobacter, E. cloacae, and the pathogenic group of Neisseria. It is inactive against Proteus, P. aeruginosa, and Gram-positive bacteria.Formal Name:...
Keywords: FR2054, 3'-benzoate bicyclomycin
Application: Antibiotic
CAS 37134-40-0
MW: 406.4 D
From 189.00€ *
Review