- Search results for Cay15743
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7 products were found matching "Cay15743"!
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Item number: Cay15374-5
Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity. Taurolidine and its metabolites mimic mannose by binding to the extracellular wall of bacteria, blocking adherence to epithelial and fibroblast cells. In addition to...
Keywords: | 4,4'-methylenebis(tetrahydro-1,2H,4-thiadiazine) 1,1,1',1'-tetraoxide |
Application: | Antimicrobial mannose mimic |
CAS | 19388-87-5 |
MW: | 284.4 D |
From 43.00€
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Item number: Cay14573-1
Nimodipine is an inhibitor of L-type voltage-gated calcium (CaV) channels. It is selective for CaV1.2 over CaV1.3 channels (IC50s = 0.139 and 2.7 µM, respectively), as well as R-, N-, and P/Q-type Cav channels at 10 µM. Nimodipine (0.72-24 nM) inhibits contractions induced by potassium, but not norepinephrine, in...
Keywords: | BAY-e 9736, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-(2-methoxyethyl) 5-(1-methylethyl)... |
Application: | Ca2+ channel antagonist |
CAS | 66085-59-4 |
MW: | 418.4 D |
From 48.00€
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Item number: Cay17543-5
GTP 14564 is an inhibitor of class III receptor tyrosine kinases (IC50s = 0.3 µM for c-Fms, c-Kit, ITD-FLT3 and 1 µM for PDGFRbeta). It is without effect against a panel of non-receptor tyrosine and serine/threonine kinases. GTP 14564 blocks the proliferation of leukemia cells stimulated with FLT3 ligand by...
Keywords: | 3-phenyl-1H-benzofuro[3,2-c]pyrazole |
Application: | Class III receptor tyrosine kinase inhibitor |
CAS | 34823-86-4 |
MW: | 234.3 D |
From 43.00€
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Item number: Cay15437-10
L-ANAP methyl ester is an esterified form of the fluorescent unnatural amino acid L-ANAP (Cay-15436). It has been used in the synthesis of L-ANAP. L-ANAP methyl ester has also been used to fluorescently label proteins in vitro through genetic encoding.Formal Name: 3-[(6-acetyl-2-naphthalenyl)amino]-L-alanine, methyl...
Keywords: | methyl (S)-3-((6-acetylnaphthalen-2-yl)amino)-2-aminopropanoate, monohydrochloride |
Application: | Fluorescent unnatural amino acid ester |
MW: | 322.8 D |
From 109.00€
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Item number: Cay15947-1
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. OTX015 is an...
Keywords: | (-)-OTX015, HY-15743,... |
Application: | BRD2 / BRD3 / BRD4 inhibitor |
CAS | 202590-98-5 |
MW: | 492 D |
From 66.00€
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Item number: Cay13574-1
The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. The 1C subfamily (AKR1C) includes four human hydroxysteroid dehydrogenases, with AKR1C1 being a 20alpha-HSD and the other three being 3alpha-HSDs. AKR1C1 metabolizes progesterone to an inactive progestin,...
Keywords: | NSC 109116, 5-bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid |
Application: | AKR1C1 inhibitor |
CAS | 4906-68-7 |
MW: | 293.1 D |
From 86.00€
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Item number: Cay31574-5
Trimebutine is an opioid receptor agonist. It binds to µ-, delta-, and kappa-opioid receptors with Ki values of 0.34, 0.5, and 0.58 µM, respectively, in canine myenteric plexus synaptosomes. Trimebutine inhibits twitch contraction and acetylcholine (ACh) release induced by low-frequency electrical stimulation in...
Keywords: | (±)-Trimebutine, 3,4,5-trimethoxy-benzoic acid, 2-(dimethylamino)-2-phenylbutyl ester |
Application: | Opioid receptor agonist |
CAS | 39133-31-8 |
MW: | 387.5 D |
From 60.00€
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