2 products were found matching "Cay15746-96"!
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TG101209
Item number: Cay14696-10
TG101209 is a potent inhibitor of the tyrosine kinases janus kinase (JAK) 2, FMS-like tyrosine kinase 3, proto-oncogene RET, and JAK3 (IC50 = 6, 25, 17, and 169 nM, respectively). Through these effects, it induces cell cycle arrest and apoptosis in leukemic cell lines and CD45+ myeloma cells.Formal Name:...
| Keywords: | N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-benzenesulfonamide |
| Application: | Tyrosine kinase inhibitor |
| CAS | 936091-14-4 |
| MW: | 509.7 D |
From 60.00€
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SU 9516
Item number: Cay14796-1
SU 9516 is a 3-substituted indolinone that has anti-proliferative and pro-apoptotic activity in tumor cells. It is a potent inhibitor of several cyclin-dependent kinases (CDKs) with selectivity for Cdk2 (IC50s = 22, 40, and 200 nM for Cdk2/cyclin A, Cdk1/cyclin B, and Cdk4/cyclin D1). It does not inhibit PKC, p38,...
| Keywords: | 1,3-dihydro-3Z-(1H-imidazol-5-ylmethylene)-5-methoxy-2H-indol-2-one |
| Application: | CDK inhibitor |
| CAS | 377090-84-1 |
| MW: | 241.3 D |
From 43.00€
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