11 products were found matching "Cay15746"!

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Oxaprozin
Oxaprozin

Item number: Cay15476-5

Oxaprozin is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 2.2 and 36 µM for human COX-1 and COX-2, respectively). It decreases acetic acid-induced writhing times and carrageenan-induced paw edema in mice when administered at doses of 100 and 70 mg/kg, respectively. Formulations...
Keywords: Daypro, NSC 310839, Wy 21743, 4,5-diphenyl-2-oxazolepropanoic acid
Application: COX1/2 inhibitor
CAS 21256-18-8
MW: 293.3 D
From 46.00€ *
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(S)-alpha-Methylbenzyl Ricinoleamide
(S)-alpha-Methylbenzyl Ricinoleamide

Item number: Cay17546-5

(S)-alpha-Methylbenzyl ricinoleamide is a fatty acid amide derived from ricinoleic acid and methyl benzylamine. It demonstrates potent growth inhibition of glioma (U251), breast (MCF-7), ovarian (NCI-ADR/RES and OVCAR-3), kidney (786-0), non-small cell lung (NCI-H460), and prostate (PC-3) cancer cells with a mean...
Keywords: 12R-hydroxy-N-[(1S)-1-phenylethyl]-9Z-octadecenamide
Application: Growth inhibition
CAS 1246776-22-6
MW: 401.6 D
From 43.00€ *
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CBX3 (human recombinant)
CBX3 (human recombinant)

Item number: Cay15467-100

The heterochromatin protein 1 (HP1) family, which consists of isoforms HP1-alpha (CBX5), HP1-beta (CBX1), and HP1-gamma (CBX3), are chromatin-associated proteins involved in gene regulation and heterochromatin formation. CBX proteins have an N-terminal chromodomain, a C-terminal chromoshadow domain, and a hinge...
Keywords: CBX3, HECH, HECH, HP1 gamma, HP1 gamma, Modifier 2 protein, Modifier 2 protein, Chromobox protein homolog 3, Chromobox...
Application: Binding assays
Expressed in: E.coli
Origin: human
465.00€ *
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Rabbit Anti-Goat IgG:Eu-W1024
Rabbit Anti-Goat IgG:Eu-W1024

Item number: Cay16574-1

Concentration: 1 mg/ml Antibody: Rabbit poyclonal anti-Goat IgG Excitation max. lambda: 340 nm Emission max. lambda: 615 nm Uses: TR-FRET and High throughput screening (HTS) applications Form: Conjugate supplied as a liquid in 50 mn Tris (pH 7.8) + 0.9% NaCl + 0.05% NaN3Emission: 615 nm. Excitation: 340 nm....
Application: Fluorescence
From 529.00€ *
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JWH 200 6-hydroxyindole metabolite
JWH 200 6-hydroxyindole metabolite

Item number: Cay10746-5

JWH 200 is an aminoalkylindole that acts as a cannabinoid (CB) receptor agonist, binding the CB1 receptor with high-affinity (IC50 = 7.8-42 nM). JWH 200 is one of several synthetic CBs which have been included in smoking mixtures. JWH 200 6-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 200...
Keywords: (6-hydroxy-1-(2-morpholinoethyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone
Application: Expected urinary JWH 200 metabolite
CAS 1427325-76-5
MW: 400.5 D
From 339.00€ *
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2,4-DMA (hydrochloride)
2,4-DMA (hydrochloride)

Item number: Cay19746-5

2,4-DMA (hydrochloride) (Cay-19746) is an analytical reference standard that is classified as an amphetamine. It is a serotonin 5-HT2 receptor agonist with an apparent pA2 value of 5.6. This product is intended for research and forensic applications.Formal Name: 2,4-dimethoxy-alpha-methyl-benzeneethanamine,...
Keywords: 2,4-Dimethoxyamphetamine, 2,4-dimethoxy-alpha-methyl-benzeneethanamine, monohydrochloride
Application: Analytical reference standard, Amphetamine, Serotonin 5-HT2 receptor agonist
CAS 33189-36-5
MW: 231.7 D
From 280.00€ *
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Lonafarnib
Lonafarnib

Item number: Cay11746-5

Farnesyltransferase drives the post-translational farnesylation of a number of target proteins, including Ras, a component of the MAPK and Akt signaling pathways involved in cell proliferation, and Ras homolog enriched in brain (Rheb), which stimulates mTOR activity. By arresting growth, farnesyltransferase...
Keywords: Sarasar, SCH 66336,...
Application: Farnesyl transferase inhibitor
CAS 193275-84-2
MW: 638.8 D
From 44.00€ *
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Abacavir (sulfate)
Abacavir (sulfate)

Item number: Cay14746-5

Abacavir is a nucleoside analog and an inhibitor of HIV-1 reverse transcriptase (Ki = 2.1 µM for the wild-type enzyme). It inhibits replication of a variety of HIV-1 and HIV-2 strains, including strains resistant to 3'-azido-3'-deoxythymidine (zidovudine, Cay-15492) or 2',3'-dideoxyinosine (didanosine, Cay-23715),...
Keywords: (1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol, monosulfate
Application: HIV type 1 reverse transcriptase inhibitor
CAS 216699-07-9
MW: 384.4 D
From 60.00€ *
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Doxofylline
Doxofylline

Item number: Cay18746-5

Doxofylline is a methylxanthine bronchodilator. It inhibits phosphodiesterase 2A1 (PDE2A1) and is an adenosine A2A receptor antagonist (IC50s = 0.74 and 0.9 mM, respectively). Doxofylline (10 µM) reduces superoxide production induced by LPS or PMA (Cay-10008014) in isolated human monocytes. It delays...
Keywords: 7-(1,3-dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
Application: PDE4 inhibitor, adenosine A1 receptor antagonist
CAS 69975-86-6
MW: 266.3 D
From 43.00€ *
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PGPC-d6
PGPC-d6

Item number: Cay25746-1

PGPC-d6 is intended for use as an internal standard for the quantification of PGPC (Cay-10044), as well as related fragmented short-chain fatty acid remnants of phospholipid oxidation, by GC- or LC-MS. PGPC is an oxidized phospholipid that can be formed under conditions of oxidative stress. It is found as a...
Keywords: 1-Palmitoyl-2-glutaryl Phosphatidylcholine-d6, (R)-2-((4-carboxybutanoyl-2,2,3,3,4,4-d6)oxy)-3-(palmitoyloxy)propyl...
Application: Oxidized phospholipid, GC-MS, LC-MS, internal standard
MW: 615.8 D
From 344.00€ *
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L,L-Dityrosine
L,L-Dityrosine

Item number: Cay35746-1

L,L-Dityrosine is an amino acid conjugate containing two L-tyrosine molecules. L-Tyrosine residues in fibrinogen proteins can form L,L-dityrosine cross-links between fibrinogen proteins in the presence of hematin and plasma-generated hydrogen peroxide under non-thermal plasma exposure. L-Tyrosine residues in human,...
Keywords: alpha3S,alpha3'S-diamino-6,6'-dihydroxy-[1,1'-biphenyl]-3,3'-dipropanoic acid
Application: Amino acid conjugate
CAS 63442-81-9
MW: 360.4 D
From 177.00€ *
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