8 products were found matching "Cay14571"!

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(R,S)-AMPA (hydrate)
(R,S)-AMPA (hydrate)

Item number: Cay14571-10

AMPA is the defining agonist for the AMPA subgroup of ionotropic glutamate receptors, which mediate excitatory neurotransmission. Because AMPA does not interfere with binding sites for kainic acid (Cay-78050) or NMDA (Cay-14581), it can be used to distinguish AMPA receptor-specific activity that contributes to a...
Keywords: alpha-amino-3-hydroxy-5-methyl-4-Isoxazolepropionic Acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic...
Application: AMPA receptor agonist
MW: 186.2 D
From 134.00€ *
Review
PB-22 7-hydroxyisoquinoline isomer
PB-22 7-hydroxyisoquinoline isomer

Item number: Cay14557-1

PB-22 (Cay-14096) is a synthetic cannabinoid that is structurally analogous to the potent aminoalkylindoles like JWH 018 (Cay-10900). It differs from JWH 018 by having 8-hydroxyquinoline replacing the naphthalene group of JWH 018. PB-22 7-hydroxyisoquinoline isomer is a structural isomer of PB-22. The physiological...
Keywords: 1-pentyl-1H-indole-3-carboxylic acid, 7-isoquinolinyl ester
Application: Analytical reference standard, synthetic cannabinoid analog, PB-22 structural isomer
CAS 2365471-61-8
MW: 358.4 D
From 109.00€ *
Review
Nimodipine
Nimodipine

Item number: Cay14573-1

Nimodipine is an inhibitor of L-type voltage-gated calcium (CaV) channels. It is selective for CaV1.2 over CaV1.3 channels (IC50s = 0.139 and 2.7 µM, respectively), as well as R-, N-, and P/Q-type Cav channels at 10 µM. Nimodipine (0.72-24 nM) inhibits contractions induced by potassium, but not norepinephrine, in...
Keywords: BAY-e 9736, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-(2-methoxyethyl) 5-(1-methylethyl)...
Application: Ca2+ channel antagonist
CAS 66085-59-4
MW: 418.4 D
From 48.00€ *
Review
11-deoxy-16,16-dimethyl Prostaglandin E2
11-deoxy-16,16-dimethyl Prostaglandin E2

Item number: Cay14570-1

11-deoxy-16,16-dimethyl Prostaglandin E2 (11-deoxy-16,16-dimethyl PGE2) is a stable synthetic analog of PGE2. It is an agonist for both EP2 and EP3 receptors. It is an effective inhibitor of gastric acid secretion and ulcer formation in the rat, with ED50 values of 1 mg/kg and 0.021 mg/kg respectively. It is 900...
Keywords: 11-deoxy-16,16-dimethyl PGE2, 9-oxo-15R-hydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid
Application: EP receptor agonist
CAS 53658-98-3
MW: 364.5 D
From 86.00€ *
Review
Citalopram (hydrobromide)
Citalopram (hydrobromide)

Item number: Cay14572-1

Citalopram is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with an IC50 value of 1.8 nM for 5-HT reuptake in rat brain synaptosomes. It is selective for 5-HT reuptake over that of dopamine and norepinephrine (IC50s = >6 mM). Citalopram potentiates headweaving and tremor induced by 5-hydroxy-L-tryptophan...
Keywords: Bonitrile, Lu 10-171B, Nitalapram, Prepram,...
Application: Serotonin reuptake inhibitor, nicotinic acetylcholine receptor antagonist
CAS 59729-32-7
MW: 405.3 D
From 442.00€ *
Review
Ro 25-6981 (maleate)
Ro 25-6981 (maleate)

Item number: Cay14578-1

Ro 25-6981 (maleate) is a potent, selective activity-dependent blocker of NMDA receptors containing the NR2B subunit (IC50s = 9 nM and 52 µM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A, respectively). Ro 25-6981 (maleate) displays neuroprotectant effects in vitro, protecting cortical neurons...
Keywords: alphaR-(4-hydroxyphenyl)-betaS-methyl-4-(phenylmethyl)-1-piperidinepropanol, 2Z-butenedioate
Application: NMDA receptor NR2B subunit antagonist
CAS 1312991-76-6
MW: 455.6 D
From 77.00€ *
Review
Adenosine 5'-(gamma-thio)-triphosphate (lithium salt)
Adenosine 5'-(gamma-thio)-triphosphate (lithium salt)

Item number: Cay14957-1

Adenosine 5'-(gamma-thio)-triphosphate (lithium salt) is a stable analog of ATP that acts as a potent agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11). It has been used to identify kinase substrates, has been implemented as a reagent in the synthesis of DNA N-acetylglucosamine analogs,...
Keywords: ATPgammaS, P'-anhydride with phosphorothioic acid adenosine 5'-(trihydrogen diphosphate), tetralithium salt
Application: ATP analog, GPCR P2Y2 / P2Y11 agonist
CAS 93839-89-5
MW: 547 D
From 42.00€ *
Review
9-cis-Retinoic Acid
9-cis-Retinoic Acid

Item number: Cay14587-1

9-cis-Retinoic acid is a natural metabolite of vitamin A, derived from the intermediate all-trans retinoic acid (Cay-11017). It potently activates all isoforms of retinoic acid receptor (RAR) (Ki = 0.5-27 nM) as well as retinoid X receptor (RXR) isoforms (Ki = 3.8-12 nM). RAR heterodimerizes with RXR, while RXR can...
Keywords: Alitretinoin, 9-cis RA, NSC 659772, Panretin, 9-cis-retinoic acid
Application: RAR and RXR activator
CAS 5300-03-8
MW: 300.4 D
From 66.00€ *
Review