- Search results for Cay17330
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12 products were found matching "Cay17330"!
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Item number: Cay17330-25
RS 504393 is a selective antagonist of the MCP-1 receptor CCR2 (IC50s = 89 nM and >100 µM for CCR2 and CCR1, respectively). It has been shown to inhibit MCP-1-stimulated chemotaxis (IC50 = 330 nM) and ischemia-reperfusion injury in kidneys.Formal Name:...
Keywords: | 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one |
Application: | CCR2 chemokine receptor antagonist |
CAS | 300816-15-3 |
MW: | 417.5 D |
From 61.00€
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Item number: Cay17730-5
Liproxstatin-1 is a ferroptosis inhibitor. It inhibits ferroptotic cell death (IC50 = 22 nM) and lipid peroxidation in mouse embryonic fibroblasts (MEFs) with an inducible knockdown of glutathione peroxidase 4 (Gpx4-/- MEFs) when used at a concentration of 50 nM. Liproxstatin-1 also inhibits ferroptosis induced by...
Keywords: | N-[(3-chlorophenyl)methyl]-spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine |
Application: | Ferroptosis inhibitor |
CAS | 950455-15-9 |
MW: | 340.9 D |
From 75.00€
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Item number: Cay17300-50
5-methoxy DET is a synthetic tryptamine designer drug structurally similar to the potent hallucinogen N,N-DMT (Cay-13959). It inhibits serotonin uptake with an IC50 value of 2.4 µM and activates 5-HT2A receptors with an EC50 value of 8.11 nM. This product is intended for forensic and research applications.Formal...
Keywords: | 5-methoxy-N,N-Diethyltryptamine, N,N-diethyl-5-methoxy-1H-indole-3-ethanamine |
Application: | Analytical reference standard, Synthetic tryptamine designer drug, 5-HT2A agonist |
CAS | 1218-40-2 |
MW: | 246.4 D |
From 280.00€
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Item number: Cay11730-5
Coumestrol is a phytoestrogen that occurs naturally in soybeans, spinach, and clover. It competitively (vs. 17beta-estradiol, Cay-10006315) binds the estrogen receptors ERalpha (IC50 = 11 nM) and ERbeta (IC50 = 2 nM) and can induce ER-dependent gene expression in isolated cells. Coumestrol is also a weak antagonist...
Keywords: | NSC 22842, 3,9-dihydroxy-6H-benzofuro[3,2-c][1]benzopyran-6-one |
Application: | Pregnane X receptor antagonist |
CAS | 479-13-0 |
MW: | 268.2 D |
From 60.00€
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Item number: Cay17336-50
Arachidonic acid (Cay-90010) is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a...
Keywords: | AA 1,2,3,4,5-13C, 5Z,8Z,11Z,14Z-eicosatetraenoic-1,2,3,4,5-13C5 acid |
Application: | MS |
MW: | 309.4 D |
From 96.00€
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Item number: Cay17332-10
FUB-JWH 018 (Cay-17332) is an analytical reference standard that is structurally classified as a synthetic cannabinoid. The physiological and toxicological properties of this compound have not been tested. This product is intended for forensic and research applications.Formal Name:...
Keywords: | [1-[(4-fluorophenyl)methyl]-1H-indol-3-yl]-1-naphthalenyl-methanone |
Application: | Analytical reference standard, synthetic cannabinoid |
CAS | 2365471-45-8 |
MW: | 379.4 D |
From 266.00€
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Item number: Cay17331-10
5,7-dichloro Tryptamine is a ring-substituted tryptamine derivative. Although the biological effects of this compound have not been reported, tryptamines substituted with fluorine at the 5-, 6-, or 7-position have been shown to have 5-HT2C receptor selectivity over both the 5-HT2A and 5-HT2B subtypes. This product...
Keywords: | 5,7-dichloro-1H-indole-3-ethanamine, monohydrochloride |
Application: | Analytical reference standard, Ring-substituted tryptamine derivative |
CAS | 94850-28-9 |
MW: | 265.6 D |
From 60.00€
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Item number: Cay17338-50
Glaucine (Cay-17338) is an analytical reference standard categorized as an antitussive. Glaucine has hallucinogenic properties. This product is intended for research and forensic applications.Formal Name: (6aS)-5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline. CAS Number: 475-81-0....
Keywords: | (+)-Glaucine, 1,2,9,10-Tetramethoxyaporphine, Boldine Dimethyl Ether, NSC 34396,... |
Application: | Analytical reference standard, antitussive, hallucinogenic, posit. allosteric 5-HT2A receptor modulator |
CAS | 475-81-0 |
MW: | 3554 D |
From 44.00€
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Item number: Cay17333-10
Temoporfin is a synthetic chlorin with light-activated actions. When administered systemically, temoporfin accumulates in tumor cells. When stimulated with light (650-652 nm) in the presence of oxygen, reactive oxygen species are generated, leading to necrosis within the tumor. Different approaches to using...
Keywords: | m-THPC, Foscan, KW 2345, 3,3',3'',3'''-(7,8-dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-phenol |
Application: | Light-activated necrosis inducer |
CAS | 122341-38-2 |
MW: | 680.8 D |
From 43.00€
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Item number: Cay17334-10
Verteporfin is a photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. It accumulates in these abnormal blood vessels and, when activated by nonthermal red light with a wavelength of 693 nm in the presence of...
Keywords: | BPD-MA, CL 318,952,... |
CAS | 129497-78-5 |
MW: | 718.8 D |
From 43.00€
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Item number: Cay17339-10
U-73122 (Cay-70740) is an inhibitor of PLC-dependent processes, however, the mechanism of action remains unclear. The IC50 values for inhibition of platelet aggregation induced by collagen or thrombin are 0.6 and 5 µM, respectively. It also exhibits inhibitory activity against HIV-1 integrase with an IC50 value of 7...
Keywords: | 1-[6-[[(17b)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-2,5-pyrrolidinedione |
Application: | PLC inhibition negative control |
CAS | 142878-12-4 |
MW: | 466.7 D |
From 43.00€
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Item number: Cay17335-10
The free fatty acid receptor 1 (FFAR1, GPR40) is highly expressed in pancreatic beta-cells and activated by medium and long-chain fatty acids. There is evidence of a link between FFAR1 (GPR40) and the ability of fatty acids to amplify glucose-stimulated insulin secretion, making this signaling pathway a potential...
Keywords: | (3S)-6-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid |
Application: | FFAR1/GPR40 agonist |
CAS | 1000413-72-8 |
MW: | 524.6 D |
From 60.00€
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