4 products were found matching "Cay13436"!
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PP242
Item number: Cay13643-1
The mammalian target of rapamycin (mTOR) is a serine-threonine kinase that is central to two protein complexes, mTORC1 and mTORC2. These complexes are differentially regulated (e.g., only mTORC1 is sensitive to rapamycin) and regulate different pathways. PP242 is an inhibitor of the active site of mTOR kinase in...
| Keywords: | 2-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol |
| Application: | mTOR kinase inhibitor |
| CAS | 1092351-67-1 |
| MW: | 308.3 D |
From 43.00€
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Mouse Anti-c-myc IgG:Alkaline Phosphatase
Item number: Cay13463-1
Mouse anti-c-myc IgG clone 9E10 (EQKLISEEDL) conjugated to Alkaline Phosphatase Antibody: Mouse monoclonal anti-c-myc IgG1, clone 9E10 (EQKLISEEDL) Clone: 9E10 (EQKLISEEDL) Enzyme: Alkaline Phosphatase Reactivity: c-myc tagged proteins Immunogen: 9E10 epitope (EQKLISEEDL) from the human c-myc protein Uses: ELISA and...
| Application: | WB |
| Host: | Mouse |
| Species reactivity: | broad |
488.00€
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Rapamycin
Item number: Cay13346-1
Rapamycin is an allosteric inhibitor of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) originally isolated from S. hygroscopicus. It interacts with FKBP prolyl isomerase 1A (FKBP12) to form a complex that binds to and inhibits the kinase activity of mTORC1. Rapamycin inhibits growth of Rh1 and Rh30...
| Keywords: | AY 22989, NSC 226080, Wy 090217,... |
| Application: | mTORC1 blocking |
| CAS | 53123-88-9 |
| MW: | 914.2 D |
From 50.00€
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S3I-201
Item number: Cay14336-5
Signal transducers and activators of transcription (STATs) are a family of latent cytoplasmic transcription factors that convey signals from the cell membrane to the nucleus. In various human tumors, STAT3 is constitutively activated by aberrant upstream tyrosine kinase activities. STAT signaling is also suspected...
| Keywords: | NSC 74859, 2-hydroxy-4-[[2-[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid |
| Application: | STAT3 inhibitor |
| CAS | 501919-59-1 |
| MW: | 365.4 D |
From 85.00€
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