REV 5901

REV 5901 is an antagonist of cysteinyl-leukotriene receptors with a Ki value of 0.7 µM for guinea pig lung membranes. It is also an inhibitor of rat neutrophil 5-LO with an IC50 value of 0.12 µM.Formal Name: alpha-pentyl-3-(2-quinolinylmethoxy)-benzenemethanol. CAS Number: 101910-24-1. Molecular Formula: C22H25NO2. Formula Weight: 335.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: acidic PBS: <50 µg/ml, basic PBS: <50 µg/ml, DMF: >36 mg/ml, DMSO: >19 mg/ml, Ethanol: >70 mg/ml, PBS pH 7.2: <50 µg/ml. SMILES: CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1. InChi Code: InChI=1S/C22H25NO2/c1-2-3-4-12-22(24)18-9-7-10-20(15-18)25-16-19-14-13-17-8-5-6-11-21(17)23-19/h5-11,13-15,22,24H,2-4,12,16H2,1H3. InChi Key: JRLOEMCOOZSCQP-UHFFFAOYSA-N.