4 products were found matching "Cay16772"!

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R-59-022
R-59-022

Item number: Cay16772-1

Diacylglycerol (DAG) kinases (DGKs) phosphorylate DAG to give phosphatidic acid (PA), reducing signaling through DAG and increasing signaling through PA. R-59-022 is an inhibitor of DGK (IC50 = 2.8 µM). This results in increased DAG-dependent PKC activity and potentiates aggregation of thrombin-stimulated platelets....
Keywords: Diacylglycerol Kinase Inhibitor I,...
Application: Diacylglycerol kinase inhibitor
CAS 93076-89-2
MW: 459.6 D
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Rhodamine 123 (chloride)
Rhodamine 123 (chloride)

Item number: Cay16672-5

Rhodamine 123 is a membrane-permeable cationic dye that is readily accumulated within living cells. It is a substrate for the efflux pump P-glycoprotein (P-gp, also known as multidrug resistance protein 1 and ABCB1) and is rapidly exported from cells with functional P-gp. As P-gp is expressed on a population of stem...
Keywords: R-22420, R-302, RH123, 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-xanthylium, monochloride
Application: Membrane-permeable cationic dye, P-glycoprotein substrate, Mitochondrial stain
CAS 62669-70-9
MW: 380.8 D
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3-acetyl-11-keto-beta-Boswellic Acid
3-acetyl-11-keto-beta-Boswellic Acid

Item number: Cay11672-1

3-acetyl-11-keto-beta-Boswellic acid is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree B. serrata (frankincense). It selectively inhibits 5-lipoxygenase (IC50 = 1.5 µM) in an enzyme-directed, nonredox, and noncompetitive manner....
Keywords: 3-O-acetyl-11-keto-beta-Boswellic acid, AKBA, (3alpha,4beta)-3-(acetyloxy)-11-oxo-urs-12-en-23-oic acid
Application: 5-lipoxygenase inhibitor
CAS 67416-61-9
MW: 512.7 D
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Fudosteine
Fudosteine

Item number: Cay16722-100

Fudosteine is a cysteine derivative that interferes with the increase in goblet cell number, expression of the mucin MUC5AC, and subsequent mucin secretion, in airways agonized with tobacco smoke, isoproterenol, lipopolysaccharide, TNF-alpha, or oxidants. Fudosteine, which is a thiol compound with antioxidant...
Keywords: SS320A, S-(3-hydroxypropyl)-L-cysteine
Application: Cysteine derivative
CAS 13189-98-5
MW: 179.2 D
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