Quercetin (hydrate)

Quercetin is an abundant flavonoid that has been isolated from a variety of fruits and vegetables and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) content, and increases total antioxidant capacity in the kidney in a mouse model of cadmium-induced autophagy. It reduces tumor growth, induces apoptosis, and halts the cell cycle at the G1 phase in an HL60 mouse xenograft model when administered at a dose of 120 mg/kg every four days. Quercetin (30 µM) also inhibits histamine release from antigen-stimulated RBL-2H3 cells and decreases the expression of TNF-alpha, IL-1beta, IL-6, and IL-8 induced by PMACI in HMC-1 cells.Formal Name: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, hydrate. CAS Number: 849061-97-8. Molecular Formula: C15H10O7 . XH2O. Formula Weight: 302.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2)(1:4): 1 mg/ml, Ethanol: 2 mg/ml. SMILES: O=C(C(O)=C(C1=CC(O)=C(O)C=C1)O2)C3=C2C=C(O)C=C3O.O. InChi Code: InChI=1S/C15H10O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6,/h1-5,16-19,21H,1H2. InChi Key: OKXFBEYCJRMINR-UHFFFAOYSA-N.