- Search results for Cay13000
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18 products were found matching "Cay13000"!
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Item number: Cay13000-100
Pterostilbene is a polyketide synthase-derived stilbene originally isolated from P. santalinus that has diverse biological activities. It reduces photooxidative leakage induced by the herbicide acifluorfen in C. sativus cotyledon disks when used at a concentration of 30 µg/ml. Pterostilbene (25 and 50 µM) inhibits...
Keywords: | trans-3,5-Dimethoxy-4'-Hydroxystilbene, 3',5'-Dimethoxy-4-Stilbenol, 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl)-phenol |
Application: | Antioxidant |
CAS | 537-42-8 |
MW: | 256.3 D |
From 74.00€
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Item number: Cay11330-1
The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin D is a cell-permeable inhibitor that binds actin filaments, but not actin monomers, to inhibit...
Keywords: | NSC 209835,... |
Application: | Cell-permeable actin polymerization inhibitor |
CAS | 22144-77-0 |
MW: | 507.6 D |
From 83.00€
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Item number: Cay13330-10
1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28...
Keywords: | PP1 Analog II, 1-(1,1-dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Application: | Analog-sensitive kinase inhibitor |
CAS | 221244-14-0 |
MW: | 331.4 D |
From 95.00€
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Item number: Cay11300-100
Methylation of lysine residues in core histones plays a critical role in regulating gene expression. Jumonji domain containing 2D (JMJD2D) catalyzes the demethylation of di- and tri-methylated forms of histone H3 at lysine residue 9 (me 2/3), leading to transcriptional repression and activation, respectively. Like...
Keywords: | KDM4D, JHDM3D, Lysine-specific demethylase 4D, Lysine-specific demethylase 4D, Jumonji domain-containing protein 2D,... |
Application: | Enzyme activity, WB |
Expressed in: | E.coli |
MW: | 42,6 kD |
642.00€
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Item number: Cay13300-10
Bisindolylmaleimide V (BIM V) is a weak inhibitor of protein kinase C (PKC) demonstrating an IC50 value >100 µM. While effectively inactive as a PKC inhibitor, BIM V blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC50 value of 8 µM.Formal Name:...
Keywords: | BIM V, Ro 31-6045, 3,4-di-1H-indol-3-yl-1-methyl-1H-pyrrole-2,5-dione |
Application: | S6K inhibitor |
CAS | 113963-68-1 |
MW: | 341.4 D |
From 86.00€
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Item number: Cay13008-50
Disuccinimidyl suberate (DSS) is a bifunctional cross-linking reagent which contains two N-hydroxysuccinimide esters that are reactive toward primary amines. DSS is membrane-permeable and is commonly used to cross-link proteins in intact cells.Formal Name: octanedioic acid, 1,8-bis(2,5-dioxo-1-pyrrolidinyl)ester....
Keywords: | DSS, NSC 340008, octanedioic acid, 1,8-bis(2,5-dioxo-1-pyrrolidinyl)ester |
Application: | Cross-linking reagent |
CAS | 68528-80-3 |
MW: | 368.3 D |
From 15.00€
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Item number: Cay13009-10
Endothelial lipase, a member of the triglyceride lipase gene family expressed in endothelial cells, prefers phospholipid-enriched high-density lipoprotein (HDL) over triglyceride as substrate. GSK264220A is a potent inhibitor of endothelial lipase (IC50 = 16 nM). Levels of HDL cholesterol are inversely correlated...
Keywords: | N-[2-methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenyl-urea |
Application: | Endothelial lipase inhibitor |
CAS | 685506-42-7 |
MW: | 363.4 D |
From 43.00€
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Item number: Cay13033-100
Valproic acid is an analog of the natural fatty acid valeric acid that inhibits class I histone deacetylases (HDACs) with an IC50 value of approximately 2 mM. It decreases the number of axon branches in sensory neurons isolated from newborn rat dorsal root ganglia, an effect that is reversed by...
Keywords: | 2-Propylvaleric Acid, Valproate, VPA, 2-propyl-pentanoic acid, monosodium salt |
Application: | HDAC inhibitor |
CAS | 1069-66-5 |
MW: | 166.2 D |
From 50.00€
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Item number: Cay13074-100
Tosyllysine chloromethylketone (TLCK) is an active site-directed agent that inhibits serine proteinases with trypsin-like activity. TLCK may also act non-selectively with thiol groups and thereby inhibit cysteine proteinases and other enzymes. To prevent proteolytic degradation, TLCK may be used in protein...
Keywords: | 1-Chloro-3-Toxylamide-7-Amino-L-2-Heptanone, TLCK, N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide,... |
Application: | Serine protease inhibitor |
CAS | 4272-74-6 |
MW: | 369.3 D |
From 77.00€
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Item number: Cay13067-100
Mitogen-activated protein kinases (MAPK) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the...
Keywords: | PB 203580, RWJ 64809, 4-[4-(4-fluorophenyl)-2-[4-methylsulfinyl)phenyl]-1H-imidazol-5-yl]-pyridine |
Application: | p38 MAPK inhibitor |
CAS | 152121-47-6 |
MW: | 377.4 D |
From 92.00€
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Item number: Cay13007-250
ethyl-2-(2-pyridyl)-4-(bromomethyl)-Thiazole-5-carboxylate is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: ethyl-4-(bromomethyl)-2-(pyridin-2-yl)thiazole-5-carboxylate. CAS Number: 1138444-37-7. Molecular Formula: C12H11BrN2O2S. Formula Weight: 327.2. Purity: >95%. Formulation: (Request...
Keywords: | ethyl-4-(bromomethyl)-2-(pyridin-2-yl)thiazole-5-carboxylate |
Application: | Synthetic intermediate, Pharmaceutical synthesis |
CAS | 1138444-37-7 |
MW: | 327.2 D |
From 22.00€
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Item number: Cay13036-500
2-(3-pyridyl)-4-methyl-Thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 4-methyl-2-(3-pyridinyl)-5-thiazolecarboxylic acid. CAS Number: 39091-01-5. Molecular Formula: C10H8N2O2S. Formula Weight: 220.3. Purity: >98%. Formulation: (Request formulation change), A...
Keywords: | 4-methyl-2-(3-pyridinyl)-5-thiazolecarboxylic acid |
Application: | Synthetic intermediate, Pharmaceutical synthesis |
CAS | 39091-01-5 |
MW: | 220.3 D |
From 22.00€
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