18 products were found matching "Cay13000"!

1 from 2 pages
No results were found for the filter!
Pterostilbene
Pterostilbene

Item number: Cay13000-50

Pterostilbene is a polyketide synthase-derived stilbene originally isolated from P. santalinus that has diverse biological activities. It reduces photooxidative leakage induced by the herbicide acifluorfen in C. sativus cotyledon disks when used at a concentration of 30 µg/ml. Pterostilbene (25 and 50 µM) inhibits...
Keywords: trans-3,5-Dimethoxy-4'-Hydroxystilbene, 3',5'-Dimethoxy-4-Stilbenol, 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl)-phenol
Application: Antioxidant
CAS 537-42-8
MW: 256.3 D
From 74.00€ *
Review
Cytochalasin D
Cytochalasin D

Item number: Cay11330-1

The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin D is a cell-permeable inhibitor that binds actin filaments, but not actin monomers, to inhibit...
Keywords: NSC 209835,...
Application: Cell-permeable actin polymerization inhibitor
CAS 22144-77-0
MW: 507.6 D
From 83.00€ *
Review
1-NM-PP1
1-NM-PP1

Item number: Cay13330-10

1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28...
Keywords: PP1 Analog II, 1-(1,1-dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Application: Analog-sensitive kinase inhibitor
CAS 221244-14-0
MW: 331.4 D
From 95.00€ *
Review
JMJD2D Strep-tagged (human recombinant)
JMJD2D Strep-tagged (human recombinant)

Item number: Cay11300-100

Methylation of lysine residues in core histones plays a critical role in regulating gene expression. Jumonji domain containing 2D (JMJD2D) catalyzes the demethylation of di- and tri-methylated forms of histone H3 at lysine residue 9 (me 2/3), leading to transcriptional repression and activation, respectively. Like...
Keywords: KDM4D, JHDM3D, Lysine-specific demethylase 4D, Lysine-specific demethylase 4D, Jumonji domain-containing protein 2D,...
Application: Enzyme activity, WB
Expressed in: E.coli
MW: 42,6 kD
642.00€ *
Review
Bisindolylmaleimide V
Bisindolylmaleimide V

Item number: Cay13300-10

Bisindolylmaleimide V (BIM V) is a weak inhibitor of protein kinase C (PKC) demonstrating an IC50 value >100 µM. While effectively inactive as a PKC inhibitor, BIM V blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC50 value of 8 µM.Formal Name:...
Keywords: BIM V, Ro 31-6045, 3,4-di-1H-indol-3-yl-1-methyl-1H-pyrrole-2,5-dione
Application: S6K inhibitor
CAS 113963-68-1
MW: 341.4 D
From 86.00€ *
Review
Disuccinimidyl Suberate
Disuccinimidyl Suberate

Item number: Cay13008-50

Disuccinimidyl suberate (DSS) is a bifunctional cross-linking reagent which contains two N-hydroxysuccinimide esters that are reactive toward primary amines. DSS is membrane-permeable and is commonly used to cross-link proteins in intact cells.Formal Name: octanedioic acid, 1,8-bis(2,5-dioxo-1-pyrrolidinyl)ester....
Keywords: DSS, NSC 340008, octanedioic acid, 1,8-bis(2,5-dioxo-1-pyrrolidinyl)ester
Application: Cross-linking reagent
CAS 68528-80-3
MW: 368.3 D
From 15.00€ *
Review
GSK264220A
GSK264220A

Item number: Cay13009-10

Endothelial lipase, a member of the triglyceride lipase gene family expressed in endothelial cells, prefers phospholipid-enriched high-density lipoprotein (HDL) over triglyceride as substrate. GSK264220A is a potent inhibitor of endothelial lipase (IC50 = 16 nM). Levels of HDL cholesterol are inversely correlated...
Keywords: N-[2-methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenyl-urea
Application: Endothelial lipase inhibitor
CAS 685506-42-7
MW: 363.4 D
From 43.00€ *
Review
Valproic Acid (sodium salt)
Valproic Acid (sodium salt)

Item number: Cay13033-100

Valproic acid is an analog of the natural fatty acid valeric acid that inhibits class I histone deacetylases (HDACs) with an IC50 value of approximately 2 mM. It decreases the number of axon branches in sensory neurons isolated from newborn rat dorsal root ganglia, an effect that is reversed by...
Keywords: 2-Propylvaleric Acid, Valproate, VPA, 2-propyl-pentanoic acid, monosodium salt
Application: HDAC inhibitor
CAS 1069-66-5
MW: 166.2 D
From 50.00€ *
Review
Tosyllysine Chloromethyl Ketone (hydrochloride)
Tosyllysine Chloromethyl Ketone (hydrochloride)

Item number: Cay13074-100

Tosyllysine chloromethylketone (TLCK) is an active site-directed agent that inhibits serine proteinases with trypsin-like activity. TLCK may also act non-selectively with thiol groups and thereby inhibit cysteine proteinases and other enzymes. To prevent proteolytic degradation, TLCK may be used in protein...
Keywords: 1-Chloro-3-Toxylamide-7-Amino-L-2-Heptanone, TLCK, N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide,...
Application: Serine protease inhibitor
CAS 4272-74-6
MW: 369.3 D
From 77.00€ *
Review
SB 203580
SB 203580

Item number: Cay13067-100

Mitogen-activated protein kinases (MAPK) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the...
Keywords: PB 203580, RWJ 64809, 4-[4-(4-fluorophenyl)-2-[4-methylsulfinyl)phenyl]-1H-imidazol-5-yl]-pyridine
Application: p38 MAPK inhibitor
CAS 152121-47-6
MW: 377.4 D
From 92.00€ *
Review
ethyl-2-(2-pyridyl)-4-(bromomethyl)-Thiazole-5-Carboxylate
ethyl-2-(2-pyridyl)-4-(bromomethyl)-Thiazole-5-Carboxylate

Item number: Cay13007-250

ethyl-2-(2-pyridyl)-4-(bromomethyl)-Thiazole-5-carboxylate is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: ethyl-4-(bromomethyl)-2-(pyridin-2-yl)thiazole-5-carboxylate. CAS Number: 1138444-37-7. Molecular Formula: C12H11BrN2O2S. Formula Weight: 327.2. Purity: >95%. Formulation: (Request...
Keywords: ethyl-4-(bromomethyl)-2-(pyridin-2-yl)thiazole-5-carboxylate
Application: Synthetic intermediate, Pharmaceutical synthesis
CAS 1138444-37-7
MW: 327.2 D
From 22.00€ *
Review
2-(3-pyridyl)-4-methyl-Thiazole-5-Carboxylic Acid
2-(3-pyridyl)-4-methyl-Thiazole-5-Carboxylic Acid

Item number: Cay13036-500

2-(3-pyridyl)-4-methyl-Thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 4-methyl-2-(3-pyridinyl)-5-thiazolecarboxylic acid. CAS Number: 39091-01-5. Molecular Formula: C10H8N2O2S. Formula Weight: 220.3. Purity: >98%. Formulation: (Request formulation change), A...
Keywords: 4-methyl-2-(3-pyridinyl)-5-thiazolecarboxylic acid
Application: Synthetic intermediate, Pharmaceutical synthesis
CAS 39091-01-5
MW: 220.3 D
From 22.00€ *
Review
1 from 2 pages