Human VEGF-C (115aa) is fused at the C-terminus to a His-tag. Lyophilized. VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a growth factor active in...

Protein function: Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively, the urea cycle takes place primarily in the liver...

(3 x 20µg). The extracellular domain of mouse TRAIL (amino acids 99-291) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge. Induces apoptosis at concentrations of >10ng/ml as tested on human tumor...

Human VEGF 165 (165aa). Lyophilized. Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to...

Human sVEGFR-1 (663aa). Lyophilized. Recombinant human soluble vascular endothelial growth factor receptor-1 (sVEGFR-1) is the naturally occurring form and is a glycosylated monomeric protein. The biological function of sVEGFR-1 seems to be an endogenous regulator of angiogenesis, binding VEGF with the same affinity...