7 products were found matching "Cay10272-250"!
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Prostratin
Item number: Cay10272-500
Activation of latent reservoirs of HIV-infected cells is a treatment strategy designed to reduce viral load and eliminate the perpetuation of retroviral infection. Prostratin is a non-tumor promoting phorbol ester that potently induces HIV-1 reactivation in latent reservoirs of infected Jurkat-LAT-GFP cells with an...
| Keywords: | 13-O-Acetylphorbol, NSC 623310, SA 101A,... |
| Application: | HIV-1 reactivation |
| CAS | 60857-08-1 |
| MW: | 390.5 D |
From 92.00€
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5,7,3',4'-Tetramethoxyflavone
Item number: Cay40272-250
5,7,3',4'-Tetramethoxyflavone is a flavone that has been found in M. paniculata and has diverse biological activities. It selectively inhibits multidrug resistance-associated protein 1 (MRP1) over MRP2 (IC50s = 7.9 and >50 µM, respectively). 5,7,3',4'-Tetramethoxyflavone (0.03-30 µM) inhibits LPS-induced nitric...
| Keywords: | 5,7,3',4'-tetramethyl Luteolin ether, Methoxyluteolin, Tetramethyl camphoral,... |
| Application: | Bioactive flavone |
| CAS | 855-97-0 |
| MW: | 342.3 D |
From 47.00€
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Strontium Ranelate
Item number: Cay30272-250
Strontium ranelate is an antiosteoporotic agent. It inhibits 1,25-dihydroxyvitamin D3-induced increases in the levels of carbonic anhydrase II and the vitronectin receptor, markers of osteoclast differentiation, in isolated chicken bone marrow cells when used at concentrations of 0.1, 0.5, and 1 mM. Pretreatment or...
| Keywords: | S12911, S12911-2, 5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-3-thiopheneacetic acid, distrontium salt |
| Application: | Antiosteoporotic agent |
| CAS | 135459-87-9 |
| MW: | 513.5 D |
From 50.00€
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SR 3335
Item number: Cay12072-25
The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORalpha, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki = 220 nM) and inhibiting constitutive transactivation...
| Keywords: | ML 176, N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide |
| Application: | RORalpha agonist |
| CAS | 293753-05-6 |
| MW: | 405.3 D |
From 43.00€
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JWH 302
Item number: Cay10722-25
JWH 302 (Cay-10722) is a cannabimimetic indole that shows 5-fold selectivity for the central cannabinoid (CB1) receptor with a Ki value of 17 nM compared to the peripheral cannabinoid (CB2) receptor (Ki = 89 nM). JWH 302 stimulates GTPgammaS binding of CB1 and CB2 receptors with EC50 values of 29.3 and 24.4 nM,...
| Keywords: | 2-(3-methoxyphenyl)-1-(1-pentyl-1H-indol-3-yl)-ethanone |
| Application: | Analytical reference standard, cannabimimetic indole |
| CAS | 864445-45-4 |
| MW: | 335.4 D |
From 276.00€
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Ursolic Acid
Item number: Cay10072-250
Ursolic acid is a pentacyclic triterpenoid that has been isolated from M. pumila and has diverse biological activities, including anticancer, hepatoprotective, anti-inflammatory, antioxidant, antimicrobial, and cardioprotective properties. It inhibits the proliferation of HepG2 liver, MCF-7 breast, and Caco-2 colon...
| Keywords: | Bungeolic Acid, Maerotaine, Malol, NSC 167406, NSC 4060, Prunol, 3beta-hydroxy-urs-12-en-28-oic acid |
| Application: | Na/K-ATPase inhibitor |
| CAS | 77-52-1 |
| MW: | 456.7 D |
From 44.00€
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(-)-WIN 55,212-3 (mesylate)
Item number: Cay12022-50
(-)-WIN 55,212-3 is an aminoalkylindole derivative which acts as a competitive neutral antagonist of the human cannabinoid CB2 receptor, blocking both the stimulating action of CP 55,940 (pA2 = 6.1) and the inverse agonism of SR 144528 (Cay-9000491) (pEC50 = 5.3). (-)-WIN 55,212-3 neither antagonizes nor mimics the...
| Keywords: | [(3S)-2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanone,... |
| Application: | Forensic studies, difuran analog |
| CAS | 131543-25-4 |
| MW: | 522.6 D |
From 56.00€
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