8 products were found matching "Cay10006788-100"!

Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGDS have been identified, namely the lipocalin-type enzyme and the hematopoietic enzyme. L-PGDS is...

8,12-iso-isoprostane F2alpha-VI-d11 (8,12-iso-iPF2alpha-VI-d11) contains 11 deuterium atoms at the 16, 16', 17, 17', 18, 18', 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of 8,12-iso-iPF2alpha-VI by GC- or LC-mass spectrometry. The relative abundance of...

Arachidonic acid-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all...

Microcystin-RR is a cyanotoxin and an inhibitor of protein phosphatase 1C (PP1C), PP1gamma, and PP2A (Kis = 0.15, 0.24, and 0.018 nM, respectively). Intratracheal administration of microcystin-RR (1,200 µg/kg) induces hepatic bleeding in mice. Microcystin-RR has been found in freshwater with cyanobacterial...

Endometriosis is common disease characterized by the presence of endometrial tissue outside the uterus which affects approximately 10% of premenopausal women. Gestrinone is a synthetic steroid used occasionally to treat endometriosis. It acts centrally on the hypothalamic-pituitary system to suppress release of...

Prostaglandin F2alpha (PGF2alpha) is the major eicosanoid product of cyclooxygenase-1 and 2 in reproductive tissues, and many others. PGF2alpha contracts bronchial smooth muscle, and regulates fertility and implantation. PGF2alpha acts through the FP receptor, a 7-transmembrane G-protein coupled receptor....

L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid...

Protein arginine deiminase 3 (PAD3) catalyzes the conversion of arginine residues to citrulline within its cellular protein substrates, which include S100A3, trichohyalin, and filaggrin, resulting in the loss of a positive charge, which can alter protein structure and/or function. It exists as a homodimer and is...