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Item number: Cay16478-10

Promethazine is a first-generation histamine H1 receptor antagonist (Ki = 0.98 nM for the human receptor). It is selective for histamine H1 over H3 and H4 receptors (Kis = >100 and 77.6 µM, respectively, for the human receptors). Promethazine also binds muscarinic acetylcholine receptors (mAChRs, Ki = 22 nM). It...

Keywords:	Diprazin, Fellozine, Lergigan, Phenergan, Romergan, N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine, monohydrochloride
Application:	H1-receptor antagonist
CAS	58-33-3
MW:	320.9 D

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