- Search results for Cay14981
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6 products were found matching "Cay14981"!
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Item number: Cay14981-5
Probenecid is a benzoic acid derivative that inhibits organic anion transporters (OATs) and the ATP-binding cassette transporter (ABCC1) multidrug resistance protein 1 (MRP1) and activates the transient receptor potential (TRP) channel TRPV2. It inhibits OAT1, OAT3, and OAT6 (Kis = 6.3, 9.0, and 8.4 µM,...
Keywords: | NSC 18786, 4-[(dipropylamino)sulfonyl]-benzoic acid |
Application: | Uricosuric, organic anion transporter inhibitor |
CAS | 57-66-9 |
MW: | 285.4 D |
From 43.00€
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Item number: Cay14986-1
Ac-DEVD-AMC is a fluorogenic substrate that can be cleaved specifically by caspase-3. Caspase activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.Formal Name:...
Keywords: | Caspase-3 Substrate (Fluorogenic), N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-Methylcoumarin,... |
Application: | Fluorogenic caspase-3 substrate |
CAS | 169332-61-0 |
MW: | 675.6 D |
From 82.00€
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Item number: Cay14987-1
Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases. At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.Formal Name:...
Keywords: | Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone,... |
Application: | Irreversible caspase-10 inhibitor |
CAS | 1135688-47-9 |
MW: | 610.6 D |
From 92.00€
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Item number: Cay14983-1
Several cyclic nucleotide phosphodiesterases (PDE2, -5, -6, -10, and -11) contain a tandem of GAF domains in their N-terminal regulatory region that are thought to mediate cAMP- or cGMP-induced stimulation of adenylyl and guanylyl cyclases. Sp-cyclic AMPS (Sp-cAMPS) is a derivative of cAMP that binds the PDE10 GAF...
Keywords: | Sp-cAMPS, cyclic 3',5'-[hydrogen (S)-phosphorothioate] adenosine, monosodium salt |
Application: | cAMP derivate, binds to PDE10 GAF domain |
CAS | 142439-95-0 |
MW: | 367.3 D |
From 92.00€
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Item number: Cay14989-1
Ac-VEID-AMC is a fluorogenic substrate based on the caspase-6 cleavage site in lamin A at amino acids VEID during apoptosis. It has also been reported to be cleaved by related proteases, including caspase-8. Caspase activity can be quantified by fluorescent detection of free AMC (also known as...
Keywords: | Caspase-6 Substrate (Fluorogenic), N-Acetyl-Val-Glu-Ile-Asp-7-amido-4-Methylcoumarin,... |
Application: | Fluorogenic caspase-6 substrate |
MW: | 673.7 D |
From 94.00€
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Item number: Cay14948-1
Calcein AM is a cell-permeable dye that, upon entering live cells, is cleaved by intracellular esterases, leaving membrane-impermeant calcein (Cay-16221), a fluorescent indicator with absorption and emission maxima of 494 and 517 nm, respectively. It can be used as an indicator of cell viability, cell-cell...
Keywords: | Calcein Acetoxymethyl ester, NSC 689290,... |
Application: | Cell-permeable dye, cell viability assays |
CAS | 148504-34-1 |
MW: | 994.9 D |
From 98.00€
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