3 products were found matching "SYN-3017-M100"!
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AZD-7762 hydrochloride
Item number: SYN-1017-M100
Soluble in DMSO or ethanol. Checkpoint kinases CHK1 and CHK2 are activated in response to DNA damage that results in cell cycle arrest, allowing sufficient time for DNA repair. Agents that lead to abrogation of such checkpoints have potential to increase the efficacy of such compounds as chemo- and radiotherapies....
| Keywords: | AZD7762 |
| Application: | CHK1/2 inhibitor |
| CAS | 1246094-78-9 |
| MW: | 398,9 D |
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Dianilinopyrimidine_01
Item number: SYN-1037-M100
Soluble in DMSO. Dianilinopyrimidine_01 is a pan tyrosine kinase inhibitor Target: Pan-Tyrosine Kinase , Substrate: Tyrosine
| Application: | Pan Tyrosine Kinase inhibitor |
| CAS | 916603-07-1 |
| MW: | 309,3 D |
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PFI-4
Item number: SYN-3047-M100
Potent and selective BRPF1 bromodomain inhibitor, with an IC50 of 80nM. PFI-4 exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. PFI-4 specifically binds to the bromodomain of BRPF1 (Kd = 13nM), inhibiting binding to tri-acetylated histone 4 (residues...
| Keywords: | N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxy benzamide |
| Application: | Potent,selective BRPF1 bromodomain inhibitor |
| CAS | 1370888-71-3 |
| MW: | 380.5 D |
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