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Pranlukast
Pranlukast

Item number: Cay10008319-10

Pranlukast is an orally bioavailable cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50s = 4.3-7.2 nM in radioligand binding assays). It is selective for the CysLT1 receptor over the CysLT2 receptor (IC50 = 3,620 nM for the human receptor). Pranlukast inhibits mucus secretion induced by leukotriene D4 (LTD4,...
Keywords: ONO-1078, ONO-RS-411, N-[4-oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4-(4-phenylbutoxy)-benzamide
Application: CysLT1 receptor antagonist
CAS 103177-37-3
MW: 481.5 D
From 26.00€ *
Review
Z-Leu-Leu-Leu-B(OH)2
Z-Leu-Leu-Leu-B(OH)2

Item number: Cay10008311-1

Z-Leu-Leu-Leu-B(OH)2 is a proteasome inhibitor with diverse biological activities. It inhibits LPS-induced expression of FMS-related tyrosine kinase 1 (FLT1) in isolated human microvascular endothelial cells and macrophages. Z-Leu-Leu-Leu-B(OH)2 (1 µM) reduces heat shock-induced increases in heat shock protein 70...
Keywords: MG 262, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1R)-1-borono-3-methylbutyl]-L-leucinamide
Application: Proteasome inhibitor
CAS 179324-22-2
MW: 491.4 D
From 401.00€ *
Review