- Search results for P4258-10.10
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8 products were found matching "P4258-10.10"!
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Item number: P4258-19Y.100
The proteins of the platelet derived growth factor (PDGF) family exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor a (PDGFRa) and PDGF receptor B (PDGFRb). PDGFra and...
Keywords: | EC=2.7.10.1, Anti-PDGFR-alpha, Anti-CD140a antigen, Anti-CD140 antigen-like family member A, Anti-Platelet-derived growth... |
Application: | FC, IF, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
From 412.00€
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Item number: P4258-15F.10
Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer. Source: Recombinant...
Keywords: | PDGFB, PDGF2, PDGF-2, Becaplermin, PDGF subunit B, Proto-oncogene c-Sis, Platelet-derived growth factor B chain,... |
Application: | ELISA |
MW: | 40261 kD |
552.00€
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Item number: P4258-15N.10
Recombinant Mouse PDGF-BB is a homodimeric, non-glycosylated, polypeptide chain containing 109 amino acids and having a molecular mass of 25kD. PDGF is a mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells...
Expressed in: | E.coli |
Origin: | mouse |
From 598.00€
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Item number: P4258-16B.10
Human PDGF-AA homodimer is produced by genetically engineered yeast, and purified by ionic exchange chromatography and reverse-phase HPLC. This polypeptide is composed of two identical polypeptide chains attached by disulfide bonds. Biological Activity: Human PDGF-AA homodimer is fully active as measured by the...
Expressed in: | Yeast |
Origin: | human |
493.00€
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Item number: P4258-18A.10
This recombinant human PDGF-BB expressed in yeast is composed of two identical polypeptide chains attached by disulfide bonds. The polypeptide chains have been partially cleaved between Arg-32 and Thr-33 (see US Patent #s 6083910 and 5895755). This cleavage is visible upon reduction of the polypeptide with a...
Expressed in: | Yeast |
Origin: | human |
416.00€
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Item number: P4258-03P.10
PDGFRa, also known as platelet derived growth factor receptor alpha, is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. This protein can bind to both A and B subunits of PDGF. It is particularly important for kidney development since mice heterozygous for the...
Keywords: | CD140a, PDGFR2, PDGFR-2, EC=2.7.10.1, PDGFR-alpha, PDGF-R-alpha, CD140a antigen, CD140 antigen-like family member A,... |
MW: | 58,4 kD |
568.00€
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Item number: P4258-20H.10
Human PDGFRb GenBank Accession No. NM_002609), cytoplasmic domain with N-terminal GST tag, expressed in a Baculovirus infected Sf9 cell expression system. Specific Activity: 3 units/ug (1 unit is defined as transfer of 1 pmol phosphate to the substrate peptide KKKSKDESVDYVPMLDMKG per minute at 30°C). Applications:...
Keywords: | CD140b, PDGFR-1, PDGFR-beta, PDGF-R-beta, EC=2.7.10.1, CD140 antigen-like family member B, Platelet-derived growth factor... |
Application: | Enzyme assays |
962.00€
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Item number: P4258-21F.10
Platelet-derived growth factor receptor (PDGFR) is a transmembrane glycoprotein of 170-185kD which undergoes homo- or heterodimerization into complexes of a and b subunits upon ligand binding, depending on the isoform of PDGF (PDGF-AA, -BB or -AB) that binds. The phosphorylation of tyrosine residues in the...
Application: | WB |
Host: | Rabbit |
Species reactivity: | mouse |
909.00€
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