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Pimozide
Pimozide

Item number: Cay16222-50

Pimozide is a dopamine receptor antagonist (Kis = 2.4, 0.3, and 1.8 nM for D2, D3, and D4 receptors, respectively). It also binds to eight additional receptors (Kds = 25-3,100 nM for the human receptors) and inhibits the voltage-gated sodium channel Nav1.2 and the voltage-gated potassium channel Kv11.1 (IC50s = 42...
Keywords: NSC 170984, R 6238, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Application: Dopamine D2/D3-receptor antagonist
CAS 2062-78-4
MW: 461.6 D
From 43.00€ *
Review
Heneicosapentaenoic Acid methyl ester
Heneicosapentaenoic Acid methyl ester

Item number: Cay11622-5

Heneicosapentaenoic Acid (HPA) is a fatty acid present in trace amounts in the green algae Bryopsis pennata Lamouroux and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA) except elongated with one carbon on the carboxyl end, placing the first double bond in the Delta6 position. HPA...
Keywords: HPA methyl ester, 6Z,9Z,12Z,15Z,18Z-heneicosapentaenoic acid, methyl ester
Application: Lipid studies
CAS 65919-53-1
MW: 330.5 D
From 145.00€ *
Review
Pellitorine
Pellitorine

Item number: Cay11662-5

Pellitorine is an amide alkaloid that has been found in P. nigrum and has diverse biological activities. Pellitorine is cytotoxic to HL-60 leukemia and MCF-7 breast cancer cells (IC50s = 13 and 1.8 µg/ml, respectively). It inhibits production of TNF-alpha, IL-1alpha, and IL-1beta and phosphorylation of ERK1/2...
Keywords: (2E,4E)-N-(2-methylpropyl)-2,4-decadienamide
Application: ACAT inhibitor
CAS 18836-52-7
MW: 223.4 D
From 37.00€ *
Review
Cyproterone Acetate
Cyproterone Acetate

Item number: Cay16622-100

Cyproterone acetate (CPA) is an androgen receptor antagonist. It binds to human androgen receptors (Ki = 14 nM) and inhibits dihydrotestosterone-induced androgen receptor activation in CV-1 cells (IC50 = 26 nM). CPA (30 mg/kg) decreases ventral prostate weight in castrated immature rats. It also suppresses accessory...
Keywords: Androcur(R), CPA, Cyprostat, NSC 81430, SH 714,...
CAS 427-51-0
MW: 416.9 D
From 60.00€ *
Review