3 products were found matching "AG-CN2-0010"!
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Phorbol 12-myristate 13-acetate
Item number: AG-CN2-0010-M001
Most commonly-used phorbol ester, Binds to and activates protein kinase C (PKC) at nM concentrations, Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors...
| Keywords: | PMA, TPA, 12-O-Tetradecanoylphorbol 13-acetate |
| Application: | PKC activator |
| CAS | 16561-29-8 |
| MW: | 616,8 D |
From 44.00€
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Atpenin A5
Item number: AG-CN2-0100-C250
Antibiotic, antifungal, potent and specific mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor, mitochondrial ATP-sensitive potassium (mK(ATP)) channel activator, cardioprotective, modulates mitochondrial ROS generation during cardioprotection
| Keywords: | 3-[(2S,4S,5R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1H)-pyridinone |
| Application: | Succinate-ubiquinone oxidoreductase inhibitor |
| CAS | 119509-24-9 |
| MW: | 366,2 D |
From 143.00€
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Amidepsine D
Item number: AG-CN2-0110-M001
Isolated from Humcola sp. FO-2942. Diacylglycerol acyltransferase (DGAT) inhibitor. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
| Application: | DGAT inhibitor |
| CAS | 79786-34-8 |
| MW: | 496,5 D |
From 275.00€
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