10 products were found matching "AG-CN2-0041"!

Anticancer compound. Chemopreventive. Shows anti-metastatic activity in prostate cancer cells through enhancement of cell-cell adhesion. Anti-invasive compound. Glycogen synthase kinase-3 beta (GSK-3 beta) inhibitor.

White to off-white powder. Soluble in DMSO, ethanol or dimethylformamide. Sparingly soluble in water. Endogenous hydrophilic bile acid, Antioxidant. Cytoprotective against oxidative stress and cell death, Hepatoprotective at cellular and molecular level, including stabilization of membranes. Protects hepatocytes...

Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase....

Antibiotic. Apoptosis inducer. Acyl-CoA:cholesterol acyltransferase inhibitor. Anticancer compound. Antihaptotactic and antimetastatic. Antiangiogenic compound. Antibacterial, antiprotozal, antiviral and antifungal compound. Shows ionophoric properties. Cytotoxic. Genotoxic. Potently interacts with ABCB1 and ABCG2...

Antibiotic Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells Mutagenic. Potent alkylating agent. Potent DNA methylating agent Nitric oxide (NO) donor. Vasorelaxant. Cytotoxic to cells that express GLUT2 glucose transporter....

Potent immunosuppressant (as cyclosporin A and rapamycin). Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2). Forms a complex with FK-506 binding protein 12 (FKBP12). Inhibits the activity of the calcium/calmodulin-dependent protein...

Antibiotic. Antibacterial (weak). Anticancer compound (weak).

N-methylated peptide that is structurally equivalent to a monomer of beauvericin (Prod. No. AG-CN2-0043). Acyl-CoA:cholesterol acyltransferase inhibitor. Platelet aggregation inhibitor. Antimicrobial. Note: The (3R,6R)-stereoisomer was shown to have anti-cancer and apoptosis inducing activity.

Antibacterial against selected Gram-positive strains, antifungal. Anticancer compound. Antileukemic. Antimitotic agent. Antiviral compound. Inhibits HIV activity. Anti-inflammatory. Synovial phospholipase A2, cyclooxygenase and lipoxygenase inhibitor. Modulator of superoxide dismutase and gluthatione peroxidase....

Isolated from Colchicum autumnale. Anti-cancer compound - Microtubule assembly inhibitor - Depolymerizes microtubules and limits microtubule formation (inactivates spindle fibre formation) - Inhibits mitosis during cell division at metaphase by inhibiting spindle formation - Anti-inflammatory compound - Suppresses...