Phentolamine (mesylate)

Phentolamine is a reversible antagonist of alpha-adrenergic receptors, non-specifically binding all alpha1- and alpha2-adrenoceptors with nanomolar affinities. Formulations containing phentolamine have been used in the treatment of hypertensive emergencies, as well as chronic and emergent pain.Formal Name: 3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-phenol, monomethanesulfonate. CAS Number: 65-28-1. Molecular Formula: C17H19N3O . CH3SO3H. Formula Weight: 377.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMSO: 30 mg/ml, Ethanol: 15 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 209, 277 nm. SMILES: CC(C=C1)=CC=C1N(C2=CC(O)=CC=C2)CC3=NCCN3.CS(O)(=O)=O. InChi Code: InChI=1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15,1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19),1H3,(H,2,3,4). InChi Key: OGIYDFVHFQEFKQ-UHFFFAOYSA-N.