- Search results for Cay16211
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14 products were found matching "Cay16211"!
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Item number: Cay16211-1
Phenoxybenzamine is an antagonist of alpha-adrenergic receptors (alpha-ARs). It inhibits norepinephrine-induced inositol phosphate formation in HEK293 cells expressing alpha1-ARs (EC50s = 125.9-316.2 nM), as well as radioligand binding to alpha2A-, alpha2B-, and alpha2C-ARs in CHO cell membranes (Kis = 60, 10, and...
Keywords: | NSC 37448, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-benzenemethanamine, monohydrochloride |
Application: | alpha2-adrenergic receptor antagonist |
CAS | 63-92-3 |
MW: | 340.3 D |
From 60.00€
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Item number: Cay11662-1
Pellitorine is an amide alkaloid that has been found in P. nigrum and has diverse biological activities. Pellitorine is cytotoxic to HL-60 leukemia and MCF-7 breast cancer cells (IC50s = 13 and 1.8 µg/ml, respectively). It inhibits production of TNF-alpha, IL-1alpha, and IL-1beta and phosphorylation of ERK1/2...
Keywords: | (2E,4E)-N-(2-methylpropyl)-2,4-decadienamide |
Application: | ACAT inhibitor |
CAS | 18836-52-7 |
MW: | 223.4 D |
From 37.00€
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Item number: Cay11622-1
Heneicosapentaenoic Acid (HPA) is a fatty acid present in trace amounts in the green algae Bryopsis pennata Lamouroux and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA) except elongated with one carbon on the carboxyl end, placing the first double bond in the Delta6 position. HPA...
Keywords: | HPA methyl ester, 6Z,9Z,12Z,15Z,18Z-heneicosapentaenoic acid, methyl ester |
Application: | Lipid studies |
CAS | 65919-53-1 |
MW: | 330.5 D |
From 145.00€
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Item number: Cay16622-1
Cyproterone acetate (CPA) is an androgen receptor antagonist. It binds to human androgen receptors (Ki = 14 nM) and inhibits dihydrotestosterone-induced androgen receptor activation in CV-1 cells (IC50 = 26 nM). CPA (30 mg/kg) decreases ventral prostate weight in castrated immature rats. It also suppresses accessory...
Keywords: | Androcur(R), CPA, Cyprostat, NSC 81430, SH 714,... |
CAS | 427-51-0 |
MW: | 416.9 D |
From 60.00€
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Item number: Cay16621-5
MitoTEMPO is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties. This compound combines the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in...
Keywords: | 2,2,6,6-tetramethyl-4-[[2-(triphenylphosphonio)acetyl]amino]-1-piperidinyloxy, monochloride, monohydrate |
Application: | Mitochondria-targeted superoxide dismutase mimetic |
CAS | 1569257-94-8 |
MW: | 528 D |
From 43.00€
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Item number: Cay16221-5
Calcein is a xanthene that is commonly used for the fluorometric determination of calcium in solution. As this form of calcein is not membrane permeable, it can be used in assays that evaluate membrane integrity. Calcein can also be used as a fluorescent indicator for fluoride, iron, and mercury. Excitation and...
Keywords: | Fluorescein Complexone, NSC 298193,... |
Application: | Fluorometric calcium indicator |
CAS | 1461-15-0 |
MW: | 622.5 D |
From 43.00€
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Item number: Cay11621-1
Menin, a product of the multiple endocrine neoplasia gene, is an essential component of histone methyltransferase complexes involving the mixed lineage leukemia (MLL) gene product. Also, the leukemogenic activity of MLL fusion proteins depends on their direct interaction with menin. MI-nc is a weak inhibitor of the...
Keywords: | 6-ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]-thieno[2,3-d]pyrimidine, dihydrochloride |
Application: | Menin-MLL inhibitor, Negative control |
CAS | 1934302-23-4 |
MW: | 405.4 D |
From 84.00€
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Item number: Cay16215-1
Taurocholic acid (TCA) is a taurine-conjugated form of the primary bile acid cholic acid (Cay-20250). Serum levels of TCA are decreased in patients with Crohn's disease and those with ulcerative colitis with no extraintestinal manifestations, but are increased in patients with ulcerative colitis accompanied by...
Keywords: | Ethanesulfonic Acid, TCA, 2-[[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic... |
Application: | Lipid emulsifier |
CAS | 145-42-6 |
MW: | 537.7 D |
From 43.00€
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Item number: Cay16216-1
Juglone is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. It has allelopathic actions, suppressing growth, photosynthesis, and respiration in plants and other organisms, although some bacteria can metabolize juglone. Juglone also irreversibly inhibits...
Keywords: | 5-Hydroxy-1,4-naphthoquinone, NSC 153189, NSC 34266, NSC 622948, 5-hydroxy-1,4-naphthalenedione |
Application: | Irreversible Pin1 inhibitor |
CAS | 481-39-0 |
MW: | 174.2 D |
From 46.00€
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Item number: Cay16210-1
5-trans PGF2alpha is the more thermodynamically stable C-5 olefin isomer of PGF2alpha and is a common impurity in commercial lots of PGF2alpha. 5-trans PGF2alpha administered intravenously to anesthetized rabbits caused a substantial (ten-fold) increase in respiratory rate, but this attribute was common to a number...
Keywords: | 5,6-trans PGF2alpha, 9alpha,11alpha,15S-trihydroxy-prosta-5E,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 36150-01-3 |
MW: | 354.5 D |
From 88.00€
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Item number: Cay16214-1
Benztropine is an antagonist of M1 muscarinic acetylcholine receptors (Ki = 0.59 nM in rat brain membranes). It is selective for M1 receptors over the serotonin transporter (Ki = 5,150 nM), however, it also binds to the dopamine transporter and inhibits dopamine reuptake (Kis = 237 and 130 nM, respectively)....
Keywords: | NSC 169913, (3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane, monomethanesulfonate |
Application: | Muscarinic cholinergic receptor antagonist |
CAS | 132-17-2 |
MW: | 403.5 D |
From 34.00€
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Item number: Cay16217-1
Guanethidine is an antihypertensive compound that competes with norepinephrine for transport into presynaptic terminals of adrenergic neurons by the norepinephrine transporter. Once guanethidine has entered the nerve, it becomes concentrated in synaptic vesicles, depleting endogenous norepinephrine, and thus,...
Keywords: | N-[2-(hexahydro-1(2H)-azocinyl)ethyl]-guanidine, monosulfate |
Application: | Antihypertensive compound |
CAS | 645-43-2 |
MW: | 296.4 D |
From 77.00€
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