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Item number: Cay14308-5

Phenamil is an inhibitor of transient receptor potential polycystin-L (TRPP3, IC50 = 140 nM) and a derivative of amiloride (Cay-14409). It also inhibits the epithelial sodium channel (ENaC, IC50 = 400 nM). Phenamil decreases basal short-circuit currents in human and ovine bronchial epithelial cells with IC50 values...

Keywords:	3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-2-pyrazinecarboxamide, monomethanesulfonate
Application:	TRPP3 inhibitor
CAS	1161-94-0
MW:	401.8 D

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