Paxilline

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
AG-CN2-0167-M001	1 mg		-		3 - 9 business days*		50.00€
AG-CN2-0167-M005	5 mg		-		3 - 9 business days*		143.00€

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Off-white solid. Soluble in DMSO, methanol or ethanol. Tremorgenic, Potent, selective and... more

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Product information "Paxilline"

Off-white solid. Soluble in DMSO, methanol or ethanol. Tremorgenic, Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium (BKCa) channels, Reversible inhibitor of inositol 1,4,5-trisphosphate receptor (InsP(3)), Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor, Liver X receptor (LXRalpha and LXRbeta, NR1H3 and NR1H2) agonist in biochemical and in vitro cell-based assays, Anticonvulsant, Apoptosis enhancer. Can sensitize various glioma cells to TRAIL-mediated apoptosis, Shown to protect neuronal cells against glutamate-induced cell death.

Keywords:	BRN 5317894, NSC 658707
Supplier:	AdipoGen Life Sciences
Supplier-Nr:	AG-CN2-0167

Properties

Application:	High-conductance calcium-activated potassium (BKCa) channel inhibitor, SERCA inhibitor
MW:	435,6 D
Formula:	C27H33NO4
Purity:	>95%
Format:	Solid

Database Information

CAS :	57186-25-1\| Matching products
KEGG ID :	K04936 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +20°C)
Signal Word:	Danger
GHS Hazard Pictograms:
H Phrases:	H301, H311, H315, H318, H331, H335
P Phrases:	P261, P280, P301+P310, P305+P351+P338, P405