PTEN (human recombinant)

PTEN (human recombinant)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10009746-50 50 µg -

6 - 10 business days*

611.00€
 
Phosphatase and tensin homology on chromosome 10 (PTEN) functions as a key regulatory enzyme in... more
Product information "PTEN (human recombinant)"
Phosphatase and tensin homology on chromosome 10 (PTEN) functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as AKT and phosphatidylinositol 3,4,5-trisphosphate (PIP3). PTEN interacts with many other proteins to regulate cell division and migration, as well as promoting apoptosis when necessary. Mutation of PTEN results in many human cancers including melanoma and prostate carcinoma, making PTEN an important tumor suppressor. PTEN is expressed in almost all tissues of the body as a 403 amino acid protein with an estimated molecular weight of 47 kDa, however the actual migration observed on western blot may vary among distinct samples.Synonyms: MMAC1, Phosphatase and Tensin Homology on Chromosome 10, Phosphatidylinositol 3-phosphatase, TEP1. Purity: >95% estimated by SDS-PAGE. Source: Human recombinant N-terminal His-tagged protein purified from Sf21 cells. MW: 50.8 kDa. Formulation: (Request formulation change), 50 mM Tris-HCl, pH 8.0, 100 mM sodium chloride, 5 mM DTT, and 20% glycerol. UniProt Accession #: P60484.
Keywords: PTEN, MMAC1, Phosphatase and tensin homolog, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, Mutated in multiple advanced cancers 1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PT
Supplier: Cayman Chemical
Supplier-Nr: 10009746

Properties

Application: Enzyme activity
Conjugate: No
MW: 50,8 kD
Purity: >95% estimated by SDS-PAGE
Format: Solution

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H301, H351
P Phrases: P201, P202, P264, P270, P280, P321, P330, P301+P310, P308+P313, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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