Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay10009746-50 | 50 µg | - |
6 - 10 business days* |
611.00€
|
Phosphatase and tensin homology on chromosome 10 (PTEN) functions as a key regulatory enzyme in... more
Product information "PTEN (human recombinant)"
Phosphatase and tensin homology on chromosome 10 (PTEN) functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as AKT and phosphatidylinositol 3,4,5-trisphosphate (PIP3). PTEN interacts with many other proteins to regulate cell division and migration, as well as promoting apoptosis when necessary. Mutation of PTEN results in many human cancers including melanoma and prostate carcinoma, making PTEN an important tumor suppressor. PTEN is expressed in almost all tissues of the body as a 403 amino acid protein with an estimated molecular weight of 47 kDa, however the actual migration observed on western blot may vary among distinct samples.Synonyms: MMAC1, Phosphatase and Tensin Homology on Chromosome 10, Phosphatidylinositol 3-phosphatase, TEP1. Purity: >95% estimated by SDS-PAGE. Source: Human recombinant N-terminal His-tagged protein purified from Sf21 cells. MW: 50.8 kDa. Formulation: (Request formulation change), 50 mM Tris-HCl, pH 8.0, 100 mM sodium chloride, 5 mM DTT, and 20% glycerol. UniProt Accession #: P60484.
Keywords: | PTEN, MMAC1, Phosphatase and tensin homolog, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, Mutated in multiple advanced cancers 1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PT |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10009746 |
Properties
Application: | Enzyme activity |
Conjugate: | No |
MW: | 50,8 kD |
Purity: | >95% estimated by SDS-PAGE |
Format: | Solution |
Database Information
KEGG ID : | K01110 | Matching products |
UniProt ID : | P60484 | Matching products |
Gene ID | GeneID 5728 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
|
H Phrases: | H301, H351 |
P Phrases: | P201, P202, P264, P270, P280, P321, P330, P301+P310, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed