3 products were found matching "Cay10009746-25"!

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PTEN (human recombinant)
PTEN (human recombinant)

Item number: Cay10009746-50

Phosphatase and tensin homology on chromosome 10 (PTEN) functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as AKT and phosphatidylinositol 3,4,5-trisphosphate (PIP3). PTEN interacts with many other proteins to regulate cell division and migration,...
Keywords: PTEN, MMAC1, Phosphatase and tensin homolog, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1,...
Application: Enzyme activity
MW: 50,8 kD
611.00€ *
Review
Maslinic Acid
Maslinic Acid

Item number: Cay10009645-25

Maslinic acid is found in a number of natural sources, most notably pomace olive oil (orujo). This pentacyclic triterpene has an antiproliferative effect against Caco-2 cancer cells (EC50 = 15 µM), HT-29 human colon cancer cells (EC50 = 74 µM), 1321N1 astrocytoma cells (IC50 = 25 µM), and human leukemia (CCRF-CEM...
Keywords: 2alpha-Hydroxyoleanoic Acid, Crategolic Acid, 2alpha,3beta-dihydroxy-olean-12-en-28-oic acid
Application: NO production inhibitor
CAS 4373-41-5
MW: 472.7 D
From 42.00€ *
Review
Leptomycin B
Leptomycin B

Item number: Cay10004976-25

Leptomycin B is a potent inhibitor of the nuclear export of proteins. It directly blocks the interaction of CRM1 (exportin 1) with nuclear export signals (NES), preventing the export of a broad range of proteins. Leptomycin B will also indirectly inhibit the export of mRNA from the nucleus by blocking the nuclear...
Keywords: Elactocin, LMB, Mantuamycin, NSC 364372,...
Application: Nuclear export blocker
CAS 87081-35-4
MW: 540.7 D
From 48.00€ *
Review