- Search results for Cay10009746-100
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8 products were found matching "Cay10009746-100"!
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Item number: Cay10006974-100
AM630 binds selectively to cannabinoid 2 (CB2) over CB1 receptors with Ki values of 31.2 and 5,152 nM, respectively. AM630 acts as an inverse agonist at CB2 receptors, attenuating the antinociceptive effects of a number of cannabinoids, and as a weak partial agonist at CB1 receptors. It decreases proliferation and...
Keywords: | 6-Iodopravodoline, [6-iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)-methanone |
Application: | CB2 receptor antagonist |
CAS | 164178-33-0 |
MW: | 504.4 D |
From 77.00€
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Item number: Cay10009746-50
Phosphatase and tensin homology on chromosome 10 (PTEN) functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as AKT and phosphatidylinositol 3,4,5-trisphosphate (PIP3). PTEN interacts with many other proteins to regulate cell division and migration,...
Keywords: | PTEN, MMAC1, Phosphatase and tensin homolog, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1,... |
Application: | Enzyme activity |
MW: | 50,8 kD |
611.00€
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Item number: Cay10009796-100
CAY10602 is an activator of sirtuin 1 (SIRT1). It inhibits LPS-induced TNF-alpha release in THP-1 cells when used at concentrations of 20 and 60 µM. CAY10602 (5 µM) decreases the expression of GPX4, SLC7A11, and SLC3A2, as well as increases the levels of iron and malondialdehyde (MDA), in A549 lung and MDA-MB-231...
Keywords: | 1-(4-fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine |
Application: | SIRT1 activator |
CAS | 374922-43-7 |
MW: | 418.4 D |
From 40.00€
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Lipid-based Drug Delivery Tools
Item number: Cay10007946-10
C16 Sphingomyelin is a naturally occurring sphingolipid. Levels of C16 sphingomyelin are elevated in the prefrontal cortex and cerebellum in a rat model of diabetes induced by streptozotocin (STZ, Cay-13104), as well as in the liver in mouse models of Niemann-Pick type C1 disease. Plasma levels of C16 sphingomyelin...
Keywords: | N-Palmitoyl-D-erythro-Sphingosylphosphorylcholine, Palmitoyl Sphingomyelin, SM(d18:1/16:0), Sphingomyelin (d18:1/16:0),... |
Application: | Bioactive Lipid Assays |
CAS | 6254-89-3 |
MW: | 703 D |
From 94.00€
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Item number: Cay10009146-1
Formulation: 1 M HEPES, pH 5.0.
Application: | Acid Phosphatase assay |
24.00€
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Item number: Cay10049-100
6(S)-Lipoxin A4 (6(S)-LXA4) is an isomer of the trihydroxy fatty acid LXA4 (Cay-90410). It is formed from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) through double lipoxygenase-catalyzed reactions initiated by either 5-lipoxygenase (5-LO) followed by 12- or 15-LO, with a leukotriene A4 (LTA4)...
Keywords: | 5(S),6(S),15(S)-TriHETE, 5(S),6(S)-Lipoxin A4, 6(S)-LXA4, 6-epi-Lipoxin A4,... |
Application: | Bioactive lipid studies |
CAS | 94292-80-5 |
MW: | 352.5 D |
From 368.00€
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Item number: Cay19706-100
Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of laurdan can be used to identify phospholipid phase. When excited at 340 nm, GP values are 0.6 and -0.2 for gel...
Keywords: | 1-[6-(dimethylamino)-2-naphthalenyl]-1-dodecanone |
Application: | Membrane permeable fluorescent probe, GP quantitation |
CAS | 74515-25-6 |
MW: | 353.5 D |
From 64.00€
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Item number: Cay10046-100
URB597 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH), the enzyme that hydrolyzes anandamide (AEA, Cay-90050) and other simple esters and amides with long unsaturated acyl chains (IC50 = 4.6 nM and 0.5 nM in brain membranes and intact neurons, respectively). URB597 exhibits both...
Keywords: | (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate |
Application: | FAAH inhibitor |
CAS | 546141-08-6 |
MW: | 338.4 D |
From 54.00€
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