- Search results for Cay10750
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11 products were found matching "Cay10750"!
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Item number: Cay10007777-500
D-myo-Inositol-1-phosphate (Ins(1)P1) is a member of the inositol phosphate (InsP) molecular family of second messengers that play a critical role in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of...
Keywords: | 1-IP1 (sodium salt), Ins(1)P1 (sodium salt), D-myo-inositol-1-hydrogen phosphate, monosodium salt |
Application: | Bioactive lipid assays |
MW: | 282.1 D |
From 85.00€
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Item number: Cay10785-50
Peptidyl arginine deiminase 2 (PAD2) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is composed of an alpha/beta propeller domain, an IgG1 domain that contains calcium...
Keywords: | PADI2, PAD-H19, PAD-H19, KIAA0994, Peptidylarginine deiminase II, Peptidylarginine deiminase II, Protein-arginine... |
Application: | Enzyme activity |
642.00€
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Item number: Cay10705-50
(±)9-HpODE is a racemic mixture of the fatty acid hydroperoxide product (9(S)-HpODE) formed from lipoxygenase action on linoleic acid. It shows antimicrobial activity against various fungal and bacterial pathogens and thus may play a role in plant defense. In mammalian species, monocyte-induced oxidization of LDL...
Keywords: | (±)9-hydroperoxy-10E,12Z-octadecadienoic acid |
Application: | Bioactive lipid studies |
CAS | 5502-91-0 |
MW: | 312.4 D |
From 134.00€
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Item number: Cay10749-50
Methylhexanamine (hydrochloride) is a simple aliphatic amine that was once marketed as a nasal decongestant (Forthane) but is now sold as a bodybuilding supplement (Floradrene, Geranamine). It is also sold as a mild stimulant in the form of party pills and has been reported to cause cerebral hemorrhage in a case...
Keywords: | Dimethylamylamine, DMAA, Floradrene, Forthane, Geranamine, NSC 1106, 4-methyl-2-hexanamine, monohydrochloride |
Application: | Analytical reference standard, Simple aliphatic amine, Nasal decongestant, Bodybuilding supplement |
CAS | 13803-74-2 |
MW: | 151.7 D |
From 232.00€
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Item number: Cay10702-50
Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. Many myeloproliferative diseases have been linked to a mutation in JAK2 where a switch from valine to phenylalanine occurs at the 617 position (V617F). AZD...
Keywords: | 5-chloro-N2-[(1S)-1-(5-fluoro-2-pyrimidinyl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine |
Application: | JAK2 inhibitor |
CAS | 935666-88-9 |
MW: | 348.8 D |
From 50.00€
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Item number: Cay10734-50
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. UNC0638 is...
Keywords: | 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine |
Application: | G9a HMTase inhibitor |
CAS | 1255580-76-7 |
MW: | 509.7 D |
From 65.00€
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Item number: Cay10743-50
Cytosolic phospholipase A2alpha (cPLA2alpha) specifically catalyzes the hydrolysis of arachidonic acid from the sn-2-ester position of membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes, both important mediators of the inflammatory process. CAY10650 is a...
Keywords: | 3-(2-methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid |
Application: | cPLA2alpha inhibitor |
CAS | 1233706-88-1 |
MW: | 471.5 D |
From 88.00€
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Item number: Cay10793-50
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which selectively inhibit PTKs of key growth factors. AG-879 is a tyrphostin compound that inhibits nerve growth factor...
Keywords: | Tyrphostin AG-879, 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-2E-propenethioamide |
Application: | Tyrosine kinase inhibitor |
CAS | 148741-30-4 |
MW: | 316.5 D |
From 86.00€
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Item number: Cay10728-50
PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such as phosphatidylinositol 3-kinase (PI3K) or PTEN. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking and initiates an intricate signaling...
Keywords: | N-[[(3-chloro-2-hydroxy-5-nitrophenyl)amino]thioxomethyl]-benzamide |
Application: | PI3K-PDK1-Akt-dependent phosphorylation inhibitor |
CAS | 53501-41-0 |
MW: | 351.8 D |
From 27.00€
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Item number: Cay10787-50
The Rho family of small GTPases play an important role in transduction of cell signaling events associated with several human cancers. CCG-1423 is a specific inhibitor of Rho pathway-mediated signaling and activation of serum response factor (SRF) transcription. The site of inhibition in the pathway is not precisely...
Keywords: | 1-[3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)-3-piperidinecarboxamide |
Application: | Rho inhibitor |
CAS | 1207113-88-9 |
MW: | 478.8 D |
From 52.00€
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Item number: Cay10736-50
(±)-WIN 55,212 is a racemic mixture of the cannabinoid (CB) receptor 1 (CB1) and CB2 agonist (+)-WIN 55,212-2 (Cay-10009023) and the CB2 neutral antagonist (-)-WIN 55,212-3 (Cay-12022). It inhibits electrically induced contractions in mouse vas deferens preparations (IC50 = 0.006 µM) and reduces prostaglandin (PG)...
Keywords: | [2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanone,... |
Application: | CB receptor agonist |
CAS | 137795-17-6 |
MW: | 522.6 D |
From 56.00€
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