PRMT1 (human recombinant)

Protein Arginine Methyltransferases (PRMTs) are S-adenosyl-L-methionine-dependent enzymes that catalyze post-translational modification of arginine residues by methylation in three different ways: monomethylation, symmetric dimethylation, or asymmetric dimethylation at terminal arginine guanidino nitrogen atoms. Class I PRMTs catalyze arginine monomethylation and asymmetric dimethylation. PRMT1 is a class I arginine methyltransferase that methylates arginine residues at a number of glycine and arginine rich regions (GAR motifs) in proteins including histone H4 at arginine 3.Synonyms: Interferon receptor 1-bound protein 4, Protein Arginine Methyltransferase 1. Purity: >35% estimated by SDS-PAGE. Source: Active recombinant N-terminal GST-tagged protein expressed in E. coli. Amino Acids: 2-371 (full-length). MW: 69.2 kDa. UniProt Accession #: Q99873.