- Search results for Cay15731
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
8 products were found matching "Cay15731"!
Close filters
Filter by:
No results were found for the filter!
Item number: Cay15573-1
Inactivation of the tumor suppressor p53 commonly coincides with increased signaling through NF-kappaB in cancer. CAY10681 is a dual modulator of p53-MDM2 interaction and NF-kappaB signaling. It potently binds MDM2 (Ki = 250 nM), reducing MDM2-mediated turnover of p53. CAY10681 also inhibits phosphorylation of...
Keywords: | 4-(4-bromophenyl)-4,5-dihydro-5-[3-(1H-imidazol-1-yl)propyl]-3-phenyl-1-(phenylmethyl)-pyrrolo[3,4-c]pyrazol-6(1H)-one |
Application: | p53-MDM2 interaction / NF-kappaB signaling modulator |
CAS | 1542066-69-2 |
MW: | 552.5 D |
From 98.00€
*
Item number: Cay15773-1
Tiotropium is an antagonist that binds to M1, M2, and M3 muscarinic acetylcholine receptors (Kds = 0.43, 0.54, and 0.69 nM, respectively, for human receptors). It decreases acetylcholine-induced contraction of isolated guinea pig trachea in a concentration-dependent manner. In vivo, tiotropium (1 g/L inhaled...
Keywords: | BA 679BR,... |
Application: | Muscarinic cholinergic receptor antagonist |
CAS | 136310-93-5 |
MW: | 472.4 D |
From 98.00€
*
Item number: Cay15073-1
Orexin A is a 33 amino acid hypothalamic neuropeptide with a role in appetite regulation, wakefulness, locomotor activity, hypothalamic-pituitary-adrenal activity, and pain thresholds. Orexin signaling is activated by nutrient depletion, causing an increase in food intake by delaying the signals of satiety. It...
Keywords: | Hypocretin 1, OXA |
Application: | HCRTR1/2 Ox1R / Ox2R ligand |
MW: | 3561.1 D |
From 385.00€
*
Item number: Cay15273-1
Aldosterone is a steroid hormone secreted by the adrenal cortex and is the principle mineralocorticoid controlling sodium and potassium balance. Its primary role is to promote unidirectional salt reabsorption in epithelial tissues. Aldosterone is synthesized from cholesterol in the zona glomerulosa of the adrenal...
Keywords: | 18-Aldocorticosterone, NSC 73856, Reichstein X, 11beta,21-dihydroxy-3,20-dioxo-pregn-4-en-18-al |
Application: | Steroid hormone, mineralocorticoid hormone |
CAS | 52-39-1 |
MW: | 360.4 D |
From 43.00€
*
Item number: Cay15373-1
Transcriptional activation by NF-kappaB is limited by IkappaBalpha binding, which masks the NF-kappaB nuclear localization signal that initiates nuclear translocation. Cytokines trigger a signaling cascade of kinases that target IkappaBalpha for degradation, enabling NF-kappaB to promote gene expression. Because...
Keywords: | 6-(phenylsulfinyl)-tetrazolo[1,5-b]pyridazine |
Application: | IkappaBalpha ubiquitination inhibitor |
CAS | 62645-28-7 |
MW: | 245.3 D |
From 66.00€
*
Item number: Cay15873-1
Dehydroepiandrosterone sulfate (DHEAS) is a metabolite of dehydroepiandrosterone that is the major secretory product of adrenal glands and is the predominant circulating precursor for active steroid hormones in humans. For example, in the fetoplacental-maternal unit, DHEAS acts as the primary precursor for placental...
Keywords: | DHA-S, DHEAS, NSC 72822, 3beta-(sulfooxy)-androst-5-en-17-one, monosodium salt |
Application: | Dehydroepiandrosterone metabolite |
CAS | 1099-87-2 |
MW: | 390.5 D |
From 50.00€
*
Item number: Cay15973-1
Prostaglandin E2 (PGE2, Cay-14010) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, inflammation, cancer, and atherosclerosis. MF498 is a selective EP4 receptor antagonist (Ki...
Keywords: | N-[[[4-(5,9-diethoxy-6,8-dihydro-6-oxo-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methyl]sulfonyl]-2-methoxy-benzeneac... |
Application: | EP4 receptor antagonist |
CAS | 915191-42-3 |
MW: | 603.7 D |
From 92.00€
*
Item number: Cay15783-1
The anaphylatoxin C3a induces a range of responses by activating its G protein-coupled receptor, C3aR, resulting in calcium mobilization. SB 290157 is a non-peptide antagonist of C3aR, competitively blocking C3a binding with an IC50 value of 200 nM. It potently inhibits a wide variety of C3a-induced responses in...
Keywords: | N2-[2-(2,2-diphenylethoxy)acetyl]-L-arginine, 2,2,2-trifluoroacetate |
Application: | C3aR antagonist |
CAS | 1140525-25-2 |
MW: | 526.5 D |
From 60.00€
*