3 products were found matching "Cay15764-96"!
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Isorhamnetin
Item number: Cay16496-10
Isorhamnetin is a natural flavonol aglycone that is the 3-methyl metabolite of quercetin (Cay-10005169). It has antioxidant activity and inhibits xanthine oxidase (IC50 = 0.40 µM). Isorhamnetin also competitively inhibits the human multidrug and toxic compounds extrusion transporter 1 (Ki = 0.32 µM), which has an...
| Keywords: | 3'-O-methyl Quercetin, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one |
| Application: | Xanthine oxidase inhibitor, MATE1 inhibitor, Antioxidant |
| CAS | 480-19-3 |
| MW: | 316.3 D |
From 68.00€
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(R)-Ibuprofen
Item number: Cay16794-500
(R)-Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) and an isomer of (±)-ibuprofen (Cay-70280). Unlike (S)-ibuprofen (Cay-16793), (R)-ibuprofen does not inhibit COX-1 or COX-2 in vitro (IC50s = 360 and 15.6 µM, respectively) but is converted to the active (S)-enantiomer in vivo. It inhibits NF-kappaB...
| Keywords: | (-)-Ibuprofen, alpha-methyl-4-(2-methylpropyl)-(alphaR)-benzeneacetic acid |
| Application: | NF-kappaB activation inhibitor |
| CAS | 51146-57-7 |
| MW: | 206.3 D |
From 104.00€
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PD 174265
Item number: Cay17649-5
PD 174265 is a potent, cell-permeable inhibitor of the tyrosine kinase activity of the epidermal growth factor (EGF) receptor (IC50 = 0.45 nM). It is effective in cells, blocking tyrosine phosphorylation induced by either EGF or heregulin (IC50s = 39 and 220 nM, respectively). The action of PD 174265 is reversible,...
| Keywords: | N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-propanamide |
| Application: | Cell-permeable EGFR inhibitor |
| CAS | 216163-53-0 |
| MW: | 371.2 D |
From 92.00€
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