8 products were found matching "Cay15730"!

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FUB-144
FUB-144

Item number: Cay15537-10

XLR11 (Cay-11565) is a synthetic cannabinoid (CB) featuring a tetramethylcyclopropyl group, which reportedly confers selectivity for the peripheral CB2 receptor over the central CB1 receptor. It also features an N-(5-fluoropentyl) chain, which increases binding to both CB receptors. FUB-144 is a derivative of XLR11...
Keywords: FUB-UR-144, [1-[(4-fluorophenyl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone
Application: Analytical reference standard, Synthetic cannabinoid XLR11 derivative
CAS 2185863-15-2
MW: 349.5 D
From 291.00€ *
Review
AKB48 N-(4-fluorobenzyl) analog
AKB48 N-(4-fluorobenzyl) analog

Item number: Cay15937-10

AKB48 (Cay-ISO00060) is a pentyl indazole with structural similarity to the synthetic cannabinoids (CBs) JWH 018 adamantyl carboxamide (Cay-9001193) and STS-135 (Cay-11564), which have been sold for recreational use. Generally, quinolones with adamantyl-carboxamide moieties display high affinity for the peripheral...
Keywords: AFUBINACA, AFB-48, FUB-AKB48, FUB-APINACA,...
Application: Analytical reference material, Synthetic cannabinoid analog
CAS 2180933-90-6
MW: 403.5 D
From 241.00€ *
Review
CRT0066101 (hydrochloride)
CRT0066101 (hydrochloride)

Item number: Cay15337-10

Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CRT0066101 is an inhibitor of all three PKD isoforms...
Keywords: 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-phenol, trihydrochloride
Application: PKD inhibitor
CAS 1781742-22-0
MW: 447.8 D
From 46.00€ *
Review
L-ANAP methyl ester (hydrochloride)
L-ANAP methyl ester (hydrochloride)

Item number: Cay15437-10

L-ANAP methyl ester is an esterified form of the fluorescent unnatural amino acid L-ANAP (Cay-15436). It has been used in the synthesis of L-ANAP. L-ANAP methyl ester has also been used to fluorescently label proteins in vitro through genetic encoding.Formal Name: 3-[(6-acetyl-2-naphthalenyl)amino]-L-alanine, methyl...
Keywords: methyl (S)-3-((6-acetylnaphthalen-2-yl)amino)-2-aminopropanoate, monohydrochloride
Application: Fluorescent unnatural amino acid ester
MW: 322.8 D
From 109.00€ *
Review
Mibefradil (hydrochloride)
Mibefradil (hydrochloride)

Item number: Cay15037-10

Mibefradil is a general calcium channel blocker that shows modest selectivity for T-type channels over L-type channels (IC50 = 2.7 and 18.6 µM, respectively). It is a potent vasodilator, increasing coronary artery flow with an EC50 value of 54 nM. Mibefradil has minimal negative inotropic effects, supporting its use...
Keywords: Posicor, Ro 40-5967,...
Application: Calcium channel blocker, Vasodilator
CAS 116666-63-8
MW: 568.6 D
From 142.00€ *
Review
Ro 106-9920
Ro 106-9920

Item number: Cay15373-10

Transcriptional activation by NF-kappaB is limited by IkappaBalpha binding, which masks the NF-kappaB nuclear localization signal that initiates nuclear translocation. Cytokines trigger a signaling cascade of kinases that target IkappaBalpha for degradation, enabling NF-kappaB to promote gene expression. Because...
Keywords: 6-(phenylsulfinyl)-tetrazolo[1,5-b]pyridazine
Application: IkappaBalpha ubiquitination inhibitor
CAS 62645-28-7
MW: 245.3 D
From 66.00€ *
Review
CAY10681
CAY10681

Item number: Cay15573-10

Inactivation of the tumor suppressor p53 commonly coincides with increased signaling through NF-kappaB in cancer. CAY10681 is a dual modulator of p53-MDM2 interaction and NF-kappaB signaling. It potently binds MDM2 (Ki = 250 nM), reducing MDM2-mediated turnover of p53. CAY10681 also inhibits phosphorylation of...
Keywords: 4-(4-bromophenyl)-4,5-dihydro-5-[3-(1H-imidazol-1-yl)propyl]-3-phenyl-1-(phenylmethyl)-pyrrolo[3,4-c]pyrazol-6(1H)-one
Application: p53-MDM2 interaction / NF-kappaB signaling modulator
CAS 1542066-69-2
MW: 552.5 D
From 98.00€ *
Review
Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt)
Orexin A amide (bovine, human, mouse, rat)...

Item number: Cay15073-1

Orexin A is a 33 amino acid hypothalamic neuropeptide with a role in appetite regulation, wakefulness, locomotor activity, hypothalamic-pituitary-adrenal activity, and pain thresholds. Orexin signaling is activated by nutrient depletion, causing an increase in food intake by delaying the signals of satiety. It...
Keywords: Hypocretin 1, OXA
Application: HCRTR1/2 Ox1R / Ox2R ligand
MW: 3561.1 D
From 385.00€ *
Review