- Search results for Cay15730
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8 products were found matching "Cay15730"!
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Item number: Cay15537-10
XLR11 (Cay-11565) is a synthetic cannabinoid (CB) featuring a tetramethylcyclopropyl group, which reportedly confers selectivity for the peripheral CB2 receptor over the central CB1 receptor. It also features an N-(5-fluoropentyl) chain, which increases binding to both CB receptors. FUB-144 is a derivative of XLR11...
Keywords: | FUB-UR-144, [1-[(4-fluorophenyl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone |
Application: | Analytical reference standard, Synthetic cannabinoid XLR11 derivative |
CAS | 2185863-15-2 |
MW: | 349.5 D |
From 291.00€
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Item number: Cay15937-10
AKB48 (Cay-ISO00060) is a pentyl indazole with structural similarity to the synthetic cannabinoids (CBs) JWH 018 adamantyl carboxamide (Cay-9001193) and STS-135 (Cay-11564), which have been sold for recreational use. Generally, quinolones with adamantyl-carboxamide moieties display high affinity for the peripheral...
Keywords: | AFUBINACA, AFB-48, FUB-AKB48, FUB-APINACA,... |
Application: | Analytical reference material, Synthetic cannabinoid analog |
CAS | 2180933-90-6 |
MW: | 403.5 D |
From 241.00€
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Item number: Cay15337-10
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CRT0066101 is an inhibitor of all three PKD isoforms...
Keywords: | 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-phenol, trihydrochloride |
Application: | PKD inhibitor |
CAS | 1781742-22-0 |
MW: | 447.8 D |
From 46.00€
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Item number: Cay15437-10
L-ANAP methyl ester is an esterified form of the fluorescent unnatural amino acid L-ANAP (Cay-15436). It has been used in the synthesis of L-ANAP. L-ANAP methyl ester has also been used to fluorescently label proteins in vitro through genetic encoding.Formal Name: 3-[(6-acetyl-2-naphthalenyl)amino]-L-alanine, methyl...
Keywords: | methyl (S)-3-((6-acetylnaphthalen-2-yl)amino)-2-aminopropanoate, monohydrochloride |
Application: | Fluorescent unnatural amino acid ester |
MW: | 322.8 D |
From 109.00€
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Item number: Cay15037-10
Mibefradil is a general calcium channel blocker that shows modest selectivity for T-type channels over L-type channels (IC50 = 2.7 and 18.6 µM, respectively). It is a potent vasodilator, increasing coronary artery flow with an EC50 value of 54 nM. Mibefradil has minimal negative inotropic effects, supporting its use...
Keywords: | Posicor, Ro 40-5967,... |
Application: | Calcium channel blocker, Vasodilator |
CAS | 116666-63-8 |
MW: | 568.6 D |
From 142.00€
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Item number: Cay15373-10
Transcriptional activation by NF-kappaB is limited by IkappaBalpha binding, which masks the NF-kappaB nuclear localization signal that initiates nuclear translocation. Cytokines trigger a signaling cascade of kinases that target IkappaBalpha for degradation, enabling NF-kappaB to promote gene expression. Because...
Keywords: | 6-(phenylsulfinyl)-tetrazolo[1,5-b]pyridazine |
Application: | IkappaBalpha ubiquitination inhibitor |
CAS | 62645-28-7 |
MW: | 245.3 D |
From 66.00€
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Item number: Cay15573-10
Inactivation of the tumor suppressor p53 commonly coincides with increased signaling through NF-kappaB in cancer. CAY10681 is a dual modulator of p53-MDM2 interaction and NF-kappaB signaling. It potently binds MDM2 (Ki = 250 nM), reducing MDM2-mediated turnover of p53. CAY10681 also inhibits phosphorylation of...
Keywords: | 4-(4-bromophenyl)-4,5-dihydro-5-[3-(1H-imidazol-1-yl)propyl]-3-phenyl-1-(phenylmethyl)-pyrrolo[3,4-c]pyrazol-6(1H)-one |
Application: | p53-MDM2 interaction / NF-kappaB signaling modulator |
CAS | 1542066-69-2 |
MW: | 552.5 D |
From 98.00€
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Item number: Cay15073-1
Orexin A is a 33 amino acid hypothalamic neuropeptide with a role in appetite regulation, wakefulness, locomotor activity, hypothalamic-pituitary-adrenal activity, and pain thresholds. Orexin signaling is activated by nutrient depletion, causing an increase in food intake by delaying the signals of satiety. It...
Keywords: | Hypocretin 1, OXA |
Application: | HCRTR1/2 Ox1R / Ox2R ligand |
MW: | 3561.1 D |
From 385.00€
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