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Item number: Cay17329-5

Picropodophyllotoxin (PPP) is a potent and selective inhibitor of the insulin-like growth factor-1 receptor (IGF-1R), blocking the phosphorylation of artificial substrates with an IC50 value of 6 nM. It does not block substrate phosphorylation by insulin receptor, EGFR, FGFR, or PDGFR. PPP inhibits IGF-1R...

Keywords:	AXL 1717, NSC 36407, Picropodophyllin, PPP,...
CAS	477-47-4
MW:	414.4 D

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