- Search results for Cay15732
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8 products were found matching "Cay15732"!
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Item number: Cay15273-5
Aldosterone is a steroid hormone secreted by the adrenal cortex and is the principle mineralocorticoid controlling sodium and potassium balance. Its primary role is to promote unidirectional salt reabsorption in epithelial tissues. Aldosterone is synthesized from cholesterol in the zona glomerulosa of the adrenal...
Keywords: | 18-Aldocorticosterone, NSC 73856, Reichstein X, 11beta,21-dihydroxy-3,20-dioxo-pregn-4-en-18-al |
Application: | Steroid hormone, mineralocorticoid hormone |
CAS | 52-39-1 |
MW: | 360.4 D |
From 43.00€
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Item number: Cay15372-5
Ebastine is a histamine H1 receptor antagonist and prodrug form of carebastine (Cay-23076). Ebastine binds to histamine H1 receptors with an IC50 value of 45 nM. It is selective for histamine H1 receptors over alpha1-adrenergic and muscarinic M1 and M2 receptors (IC50s = 183, 1,100, and >10,000 nM, respectively), as...
Keywords: | LAS-W 090, RP 64305, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone |
Application: | Histamine receptor H1 antagonis |
CAS | 90729-43-4 |
MW: | 469.7 D |
From 82.00€
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Item number: Cay15173-25
Alkaline phosphatases catalyze the hydrolysis of phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. Three isozymes of alkaline phosphatases have been identified in humans, two of which are tissue-specific placental alkaline phosphatase (PLAP), intestinal alkaline...
Keywords: | CID-25067483, 1-(3,4-dihydroxyphenyl)-2-(2-ethyl-1H-imidazol-1-yl)-ethanone, monohydrochloride |
Application: | PLAP inhibitor |
CAS | 1135318-57-8 |
MW: | 282.7 D |
From 60.00€
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Item number: Cay15573-25
Inactivation of the tumor suppressor p53 commonly coincides with increased signaling through NF-kappaB in cancer. CAY10681 is a dual modulator of p53-MDM2 interaction and NF-kappaB signaling. It potently binds MDM2 (Ki = 250 nM), reducing MDM2-mediated turnover of p53. CAY10681 also inhibits phosphorylation of...
Keywords: | 4-(4-bromophenyl)-4,5-dihydro-5-[3-(1H-imidazol-1-yl)propyl]-3-phenyl-1-(phenylmethyl)-pyrrolo[3,4-c]pyrazol-6(1H)-one |
Application: | p53-MDM2 interaction / NF-kappaB signaling modulator |
CAS | 1542066-69-2 |
MW: | 552.5 D |
From 98.00€
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Item number: Cay15973-25
Prostaglandin E2 (PGE2, Cay-14010) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, inflammation, cancer, and atherosclerosis. MF498 is a selective EP4 receptor antagonist (Ki...
Keywords: | N-[[[4-(5,9-diethoxy-6,8-dihydro-6-oxo-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methyl]sulfonyl]-2-methoxy-benzeneac... |
Application: | EP4 receptor antagonist |
CAS | 915191-42-3 |
MW: | 603.7 D |
From 92.00€
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Item number: Cay15773-25
Tiotropium is an antagonist that binds to M1, M2, and M3 muscarinic acetylcholine receptors (Kds = 0.43, 0.54, and 0.69 nM, respectively, for human receptors). It decreases acetylcholine-induced contraction of isolated guinea pig trachea in a concentration-dependent manner. In vivo, tiotropium (1 g/L inhaled...
Keywords: | BA 679BR,... |
Application: | Muscarinic cholinergic receptor antagonist |
CAS | 136310-93-5 |
MW: | 472.4 D |
From 98.00€
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Item number: Cay15783-25
The anaphylatoxin C3a induces a range of responses by activating its G protein-coupled receptor, C3aR, resulting in calcium mobilization. SB 290157 is a non-peptide antagonist of C3aR, competitively blocking C3a binding with an IC50 value of 200 nM. It potently inhibits a wide variety of C3a-induced responses in...
Keywords: | N2-[2-(2,2-diphenylethoxy)acetyl]-L-arginine, 2,2,2-trifluoroacetate |
Application: | C3aR antagonist |
CAS | 1140525-25-2 |
MW: | 526.5 D |
From 60.00€
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Item number: Cay21573-1
(-)-Caryophyllene oxide is a bicyclic sesquiterpene and a metabolite of beta-caryophyllene that has been found in C. sativa and has anticancer properties. Unlike beta-caryophyllene, (-)-caryophyllene oxide does not bind to the cannabinoid (CB) receptor CB2 (Ki = >20 µM). It induces calcium currents in HL-60 cells...
Keywords: | BCP oxide, beta-Caryophyllene epoxide, beta-Caryophyllene oxide,... |
Application: | Anticancer agent, C. sativa volatile component sensed by narcotic detection dogs |
CAS | 1139-30-6 |
MW: | 220.4 D |
From 48.00€
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