- Search results for SYN-1177-M100
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
14 products were found matching "SYN-1177-M100"!
Close filters
Filter by:
No results were found for the filter!
Item number: SYN-1077-M100
Soluble in DMSO or ethanol. SB-590885 is a novel, potent and selective small molecule inhibitor of B-Raf kinase, with a Ki of 0.16nM. It shows an 11-fold greater selectivity for B-Raf over c-Raf. It was used to address the dependence of MAPK signalling and tumor cell growth on B-Raf kinase activity. Target: ARaf -...
Keywords: | SB-590885 |
Application: | BRAF inhibitor |
CAS | 405554-55-4 |
MW: | 453,5 D |
Please request pricing for this article.
Item number: SYN-1137-M100
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. XL765 is active against class I PI3K (IC(50) = 39, 113, 9 and 43nM for p110alpha, beta, gamma and delta, respectively). XL765 also inhibits DNA-PK (IC(50) = 150nM) and mTOR (IC(50) = 157nM. Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
Keywords: | SAR-245409 |
Application: | PI3K / DNA-PK / mTOR inhibitor |
CAS | 1349796-36-6 |
MW: | 599,7 D |
Please request pricing for this article.
Item number: SYN-1157-M100
Soluble in DMSO or ethanol. MLN0128 is a potent and selective mTOR inhibitor with an IC(50) of 1nM, >200-fold less potent to class I PI3K isoforms, superior in blocking mTORC1/2 and sensitive to pro-invasion genes (vs Rapamycin).
Keywords: | MLN-0128, INK-128 |
Application: | mTOR inhibitor |
CAS | 1224844-38-5 |
MW: | 309,3 D |
Please request pricing for this article.
Item number: SYN-1173-M100
Soluble in DMSO or ethanol. SCH900776 is a selective Chk1 inhibitor with an IC(50) of 3nM. It shows 50-fold selectivity for Chk1 versus Chk2. Target: Chk1 , Kinase Group: CAMK , Substrate: Serine-Threonine
Keywords: | MK-8776 |
Application: | Chk1 inhibitor |
CAS | 891494-63-6 |
MW: | 376,3 D |
Please request pricing for this article.
Item number: SYN-1179-M100
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl, Lyn inhibitor with IC(50) values of 5.8nM and 19nM, respectively.
Keywords: | NS-187, INNO-406 |
Application: | Bcr-Abl / Lyn inhibitor |
CAS | 859212-16-1 |
MW: | 576,6 D |
Please request pricing for this article.
Item number: SYN-1170-M100
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. GSK1120212 (JTP-74057, trametinib) is a highly specific and potent MEK1 and MEK2 inhibitor with IC(50) values of 0.92nM and 1.8nM respectively. Target: MEK1 - MEK2 , Kinase Group: STE , Substrate: Serine-Threonine
Keywords: | JTP-74057, GSK212, Trametinib |
Application: | MEK1 / MEK2 inhibitor |
CAS | 871700-17-3 |
MW: | 615,4 D |
Please request pricing for this article.
Item number: SYN-1175-M100
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. IPI-145 is a potent, oral inhibitor of Class I phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma (IC(50) of 243 pM and 50nM), and is clinically active in patients with advanced hematological malignancies. Target: PI3K , Kinase Group: Atypical (PIKK) ,...
Keywords: | IPI 145 |
Application: | PI3K gamma / delta inhibitor |
CAS | 1201438-56-3 |
MW: | 416,9 D |
Please request pricing for this article.
Item number: SYN-1187-M100
Soluble in DMSO. MPI-0479605 inhibits TTK kinase activity in vitro with an IC(50) of 4nM.
Keywords: | MPI0479605 |
Application: | TTK inhibitor |
CAS | 1246529-32-7 |
MW: | 444,0 D |
Please request pricing for this article.
Item number: SYN-1197-M100
Soluble in DMSO. BLZ945 is an orally active, potent and selective CSF-1R inhibitor, which inhibits CSF-1R activity with an IC(50) of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRbeta ) as well as more than...
Keywords: | BLZ945 |
Application: | CSF1R / c-FMS inhibitor |
CAS | 953769-46-5 |
MW: | 398,5 D |
Please request pricing for this article.
Item number: SYN-1107-M100
Soluble in DMSO or ethanol. TG-89 is a JAK inhibitor. It has IC(50) values of 6, 25, 17 and 169nM against JAK2, FLT3, RET and JAK3 respectively. Target: JAK2 , Kinase Group: PTK , Substrate: Tyrosine
Keywords: | TG89 |
Application: | JAK2 / FLT3 / RET / JAK3 inhibitor |
CAS | 936091-56-4 |
MW: | 510,7 D |
Please request pricing for this article.
Item number: SYN-1147-M100
Soluble in DMSO. Bentamapimod (AS602801) is a novel and orally active c-Jun-N-Terminal Kinase Inhibitor highly specific for JNK kinases. The inhibitor Bentamapimod (AS602801) is a potent anti-inflammatory agent which has been shown to reduce the disease burden in several pre-clinical models for endometriosis, and...
Keywords: | AS-602801 |
Application: | JNK inhibitor |
CAS | 848344-36-5 |
MW: | 457,6 D |
Please request pricing for this article.
Item number: SYN-1167-M100
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. AZD2014 is a dual mTORC1/mTORC2 inhibitor for the treatment of advanced solid malignancies. Target: mTOR , Kinase Group: Atypical (PIKK) , Substrate: Serine-Threonine
Keywords: | AZD2014 |
Application: | mTOR inhibitor |
CAS | 1009298-59-2 |
MW: | 462,5 D |
Please request pricing for this article.