PF-04708671

PF-04708671
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay15018-10 10 mg -

6 - 10 business days*

125.00€
Cay15018-25 25 mg -

6 - 10 business days*

292.00€
Cay15018-50 50 mg -

6 - 10 business days*

551.00€
Cay15018-100 100 mg -

6 - 10 business days*

975.00€
 
P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and... more
Product information "PF-04708671"
P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-04708671 is a specific, cell-permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, MSK, or RSK, or many other unrelated kinases, under conditions in which it inhibits S6K1 activity. It is useful in evaluating the role of S6K1 and, indirectly, mTORC1, in cell signaling.Formal Name: 2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole. CAS Number: 1255517-76-0. Molecular Formula: C19H21F3N6. Formula Weight: 390.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 3 mg/ml, Ethanol: 2 mg/ml. lambdamax: 256, 282 nm. SMILES: CCC1=CN=CN=C1N(CC2)CCN2CC3=NC4=CC(C(F)(F)F)=CC=C4N3[H]. InChi Code: InChI=1S/C19H21F3N6/c1-2-13-10-23-12-24-18(13)28-7-5-27(6-8-28)11-17-25-15-4-3-14(19(20,21)22)9-16(15)26-17/h3-4,9-10,12H,2,5-8,11H2,1H3,(H,25,26). InChi Key: FBLPQCAQRNSVHB-UHFFFAOYSA-N.
Keywords: 2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole
Supplier: Cayman Chemical
Supplier-Nr: 15018

Properties

Application: S6K1 inhibitor
MW: 390.4 D
Formula: C19H21F3N6
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 1255517-76-0| Matching products
KEGG ID : K04688 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H301
P Phrases: P264, P270, P301+310, P321, P330, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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