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Item number: Cay15016-5

Prostaglandin E2 (PGE2) evokes distinct responses through four different 'E prostanoid' (EP) receptors. EP2 is a G protein-coupled receptor which signals preferentially through Gs proteins. PF-04418948 is an orally active, potent, and selective EP2 receptor antagonist (IC50 = 16 nM). It is over a thousand-fold less...

Keywords:	1-(4-fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-3-azetidinecarboxylic acid
Application:	EP2 receptor antagonist
CAS	1078166-57-0
MW:	409.4 D

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