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Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag. Lyophilized. Contains PBS.... more
Product information "PEDF (mouse) (rec.)"
Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag. Lyophilized. Contains PBS. Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.
Keywords: | Pedf, PEDF, SDF-3, Caspin, Serpinf1, Serpin F1, Stromal cell-derived factor 3, Pigment epithelium-derived factor |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-40B-0118 |
Properties
Application: | Bioassay |
Conjugate: | No |
Host: | Hamster cells |
Species reactivity: | mouse |
MW: | 47 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K19614 | Matching products |
UniProt ID : | P97298 | Matching products |
Gene ID | GeneID 20317 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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