PDE1C Assay Kit

PDE1C Assay Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-60312 96 rxns - -

3 - 15 business days*

599.00€
 
Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP... more
Product information "PDE1C Assay Kit"
Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE1C is a calmodulin-dependent PDE that is expressed principally in human myocardium. The PDE1C Assay Kit is designed for identification of PDE1C inhibitors using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE1C to the binding agent. The PDE1C inhibitor screening assay kit comes in a convenient 96-well format, including purified PDE1C enzyme, fluorescently labeled PDE1C substrate (cAMP), binding agent, and PDE assay buffer for 100 enzyme reactions. The key to the PDE1C Assay Kit is the specific binding agent. Using this kit, only two simple steps on a microtiter plate are required for PDE1C reactions. First, the fluorescently labeled cAMP is incubated with a sample containing PDE1C for 1 hour. Second, a binding agent is added to the reaction mix to produce a change in fluorescent polarization that can then be measured using a fluorescence reader.
Keywords: inhibitor screening, assay kit, PDE1C,
Supplier: BPS Bioscience
Supplier-Nr: 60312

Properties

Application: Enzyme kinetics, inhibitor screening, HTS
Species reactivity: human
Format: Homog.

Handling & Safety

Storage: vT
Shipping: -80°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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