PDE10A assay kit

PDE10A assay kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-60400 96 rxns - -

3 - 15 business days*

599.00€
 
The PDE10A Assay Kit is designed for identification of PDE10A inhibitors using fluorescence... more
Product information "PDE10A assay kit"
The PDE10A Assay Kit is designed for identification of PDE10A inhibitors using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE10A to the binding agent. PDE10A is a dual substrate PDE highly expressed in striatal medium spiny neurons. PDE10A inhibitors have the potential to improve the cognitive symptoms of schizophrenia. The PDE10A inhibitor screening assay kit comes in a convenient 96-well format, with purified PDE10A enzyme, fluorescently labeled PDE10A substrate (cAMP), binding agent, and PDE assay buffer for 100 enzyme reactions. The key to the PDE10A Assay Kit is the specific binding agent. Using this kit, only two simple steps on a microtiter plate are required for PDE10A reactions. First, the fluorescently labeled cAMP is incubated with a sample containing PDE10A for 1h. Second, binding agent is added to the reaction mix to produce a change in fluorescent polarization that can then be measured using a fluorescence reader.
Keywords: inhibitor screening, assay kit, PDE10A,
Supplier: BPS Bioscience
Supplier-Nr: 60400

Properties

Application: PDE10A assays, inhibitor screening, FP
Format: Homog.

Handling & Safety

Storage: vT
Shipping: vT (International: vT)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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