- Search results for Cay13032-1
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4 products were found matching "Cay13032-1"!
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Item number: Cay13032-10
The fibroblast growth factor receptors (FGFRs) are cell surface receptors with intrinsic tyrosine kinase activity, which is necessary for receptor activation and signal propagation. PD 173074 is a potent and selective inhibitor of FGFR tyrosine kinase activity, blocking autophosphorylation of FGFR1 with an IC50...
Keywords: | N-[2-[[4-(diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-urea |
Application: | FGFR inhibitor |
CAS | 219580-11-7 |
MW: | 523.7 D |
From 53.00€
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Item number: Cay13031-25
SB-431542 is a potent and selective inhibitor of the TGF-beta1 receptor ALK5 (IC50 = 94 nM). It is a less potent antagonist of ALK4 (IC50 = 140 nM) and ALK7. It does not affect the BMP receptors ALK2, ALK3, ALK6, or a panel of other kinases tested. SB-431542 specifically blocks Smad signaling, reducing gene...
Keywords: | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide, hydrate |
Application: | ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor |
MW: | 384.4 D |
From 43.00€
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Item number: Cay30321-1
Piribedil is a dopamine receptor agonist. It binds to dopamine D2, D3, and D4 receptors (IC50s = 1-1,000 nM in radioligand binding assays). Piribedil (1 and 10 mg/kg) enhances spontaneous object recognition in young adult rats and attenuates age-related memory impairments in the radial arm maze in mice. It reduces...
Keywords: | 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-pyrimidine |
Application: | Dopamine receptor agonist |
CAS | 3605-01-4 |
MW: | 298.3 D |
From 98.00€
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Item number: Cay13321-1
Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. During cancer progression both MMP-2 and MMP-9 play a role in metastatic tumor dispersion and angiogenesis. ARP 100 is a...
Keywords: | Matrix Metalloproteinase-2 Inhibitor III, CAY10609, MMP-2 Inhibitor III,... |
Application: | MMP-2 inhibitor |
CAS | 704888-90-4 |
MW: | 364.4 D |
From 39.00€
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