PCSK9(D374T)-LDLR TR-FRET Assay Kit

PCSK9(D374T)-LDLR TR-FRET Assay Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-72011 384 rxns - -

3 - 15 business days*

1,122.00€
 
The PCSK9(D374T)-LDLR TR-FRET Assay Kit is designed to measure the inhibition of the high... more
Product information "PCSK9(D374T)-LDLR TR-FRET Assay Kit"
The PCSK9(D374T)-LDLR TR-FRET Assay Kit is designed to measure the inhibition of the high affinity PCSK9 mutant (D374T) binding to LDLR in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple, a sample containing europium-labeled (Eu) LDLR ectodomain, dye-labeled acceptor, biotin-labeled PCSK9(D374T), and an inhibitor is incubated for two hours. Then, the fluorescence intensity is measured using a fluorescence reader.
Keywords: PC9, PCSK9, NARC1, NARC-1, PSEC0052, EC=3.4.21.-, Proprotein convertase 9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1, Proprotein convertase subtilisin/kexin type 9,
Supplier: BPS Bioscience
Supplier-Nr: 72011

Properties

Application: Inhibitor screening, drug discovery, HTS
Species reactivity: human
Format: Homog.

Handling & Safety

Storage: -20°C
Shipping: -80°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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