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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BPS-72011 | 384 rxns | - | - |
3 - 15 business days* |
1,122.00€
|
The PCSK9(D374T)-LDLR TR-FRET Assay Kit is designed to measure the inhibition of the high... more
Product information "PCSK9(D374T)-LDLR TR-FRET Assay Kit"
The PCSK9(D374T)-LDLR TR-FRET Assay Kit is designed to measure the inhibition of the high affinity PCSK9 mutant (D374T) binding to LDLR in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple, a sample containing europium-labeled (Eu) LDLR ectodomain, dye-labeled acceptor, biotin-labeled PCSK9(D374T), and an inhibitor is incubated for two hours. Then, the fluorescence intensity is measured using a fluorescence reader.
Keywords: | PC9, PCSK9, NARC1, NARC-1, PSEC0052, EC=3.4.21.-, Proprotein convertase 9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1, Proprotein convertase subtilisin/kexin type 9, |
Supplier: | BPS Bioscience |
Supplier-Nr: | 72011 |
Properties
Application: | Inhibitor screening, drug discovery, HTS |
Species reactivity: | human |
Format: | Homog. |
Database Information
KEGG ID : | K13050 | Matching products |
UniProt ID : | Q8NBP7 | Matching products |
Gene ID | GeneID 255738 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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