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Item number: Cay16272-5

Jumonji AT-rich interactive domain 1 (JARID1) demethylases mediate the removal of methyl groups from trimethylated lysine 4 on histone 3 (H3K4me3). PBIT is a reversible, cell-permeable inhibitor of JARID1 family demethylases (IC50s = 6, 3, 4.9, and 28 µM for JARID1A, JARID1B, JARID1C, and JARID1D, respectively). It...

Keywords:	2-p-tolyl-1,2-Benzisothiazolin-3-one, 2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one
Application:	JARID1B inhibitor
CAS	2514-30-9
MW:	241.3 D

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